GMS 6552 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
0 view 0 purchase
Course
GMS6552
Institution
GMS6552
GMS 6552 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
Which type of receptor most often utilizes second-messenger systems in its signaling?
G-protein coupled receptors
Assume you have receptor antagonists that are able to stop receptor signaling immediately. For which type of rece...
Which type of receptor most often utilizes second-messenger systems in its
signaling?
G-protein coupled receptors
Assume you have receptor antagonists that are able to stop receptor signaling
immediately. For which type of receptor would it take the longest to see the
effects of your drug at the cellular level?
Nuclear receptors
For which type of receptor would having adequate membrane permeability of an
agonist be most critical?
Nuclear receptors
Is it more likely for a G-protein coupled receptor agonist to bind near the N- or C-
terminus of the receptor?
N-terminus
Is it more likely to find a GPCR bound to a G-protein that is also bound to GTP or
GDP?
GDP
Which protein ultimately is translocated from the cytoplasm to the nucleus as a
result of JAK signaling?
STAT
, Where, in relation to the protein-coding region of a gene, are the binding sites
that become occupied by nuclear receptors?
Upstream
The levels of which second-messenger would be expected to increase following
administration of nitroglycerin?
cGMP
Does TGF-b treatment cause cells to grow more or less in the soft agar assay?
More
The latent TGF-b must be cleaved by what protease in order to be activated?
Plasmin
In the TGF-b pathway, which protein becomes activated first upon binding of a
ligand?
TGFbR2
How many DNA binding domains do SMADs have?
1
Different SMAD complexes bind different genes. Which group of SMADs is
responsible for this specificity?
R-SMADs
Would it likely be most beneficial for an early tumor to up- or down-regulate the
TGF-b pathway?
Down-regulate
Would it likely be most beneficial for a large, well-developed tumor to up- or
down-regulate the TGF-b pathway?
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller NurseAdvocate. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.49. You're not tied to anything after your purchase.
