Exam 1- Nagelhout ACTUAL Questions and CORRECT Answers
0 view 0 purchase
Course
Nagelhout
Institution
Nagelhout
Exam 1- Nagelhout ACTUAL Questions
and CORRECT Answers
Pharmacology - CORRECT ANSWER - the study of the effect of chemicals on living
tissue
Pharmacokinetics - CORRECT ANSWER - study of absorption, distribution, metabolism,
elimination of drugs
Pharmaceutics - CORRECT ANSWER - the formulat...
Pharmacokinetics is the _____ - _____ relationship. - CORRECT ANSWER - dose-
concentration relationship
Pharmacodynamics is the _____ - _______ relationship - CORRECT ANSWER -
concentration-effect relationship
The biophase is the _______ - _______ relationship - CORRECT ANSWER - plasma-
effect site relationship
- the link between PK and PD!
What are the safety issues unique to clinical anesthesia pharmacology? - CORRECT
ANSWER - 1. very low TI drugs (high potency)
2. severe consequences for over/under dosing
3. necessity for frequently adjust level of drug effect
What are the efficiency issues unique to clinical anesthesia pharmacology? - CORRECT
ANSWER - need to produce quick onset and offset of drug effect
, Ligand - CORRECT ANSWER - chemical substance that binds to a specific receptor
stereospecifity - CORRECT ANSWER - 3D shape of drug and receptor that allows them
to bind
What are the 2 types of ligands and their definitions? - CORRECT ANSWER - 1. Agonists
- binds and STIMULATES the function of the receptor
ex: B-receptor on SA node, epi, NE stimulates
2. Antagonists
- bind to and BLOCKS the function of the receptor
What are the 2 types of antagonist binding? - CORRECT ANSWER - 1. competitive =
reversible (most drugs!)
2. noncompetitive = nonreversible
ex: ASA
ED50 - CORRECT ANSWER - EFFECTIVE DOSE in 50% of the population
TD50 - CORRECT ANSWER - TOXIC DOSE in 50% of the population
LD50 - CORRECT ANSWER - LETHAL DOSE in 50% of the population
LD50/ED50 - CORRECT ANSWER - THERAPEUTIC INDEX!
- want high TI
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller MGRADES. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.49. You're not tied to anything after your purchase.