GMS 6530 ANTICOAGULANTS & CHOLESTEROL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
4 views 0 purchase
Course
GMS6530
Institution
GMS6530
GMS 6530 ANTICOAGULANTS & CHOLESTEROL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
Low molecular weight heparins
Smaller forms of heparin with better bioavailability and longer half lives
Are given by SQ injection
Levels can be followed using anti-Xa activity
Contraindic...
Smaller forms of heparin with better bioavailability and longer half lives
Are given by SQ injection
Levels can be followed using anti-Xa activity
Contraindicated in renal disease
Examples
Enoxaparin (Lovenox)
Deltaparin (Fragmin)
Fondaparinux (Arixtra)
Unfractionated heparin
Activates antithrombin III in the plasma
Antithrombin inhibits thrombin (IIa), IXa, Xa.
Not effective orally, given s.c. or i.v.
, Has a rapid onset of action when given parenterally
Structure is a sulfated glycosaminoglycan
Used for immediate anticoagulation (for example therapy in myocardial infarction)
Other uses: venous thrombosis, pulmonary embolism, thrombosis prophylaxis
Used for first 7-10 days followed by warfarin with a 3-5 day overlap
Monitored in past by partial thromboplastin time (PTT) and now more recently by
heparin levels
Can cause Heparin Induced Thrombocytopenia (HIT)
in ~1-4% of patients → STOP heparin!! (+ direct IIa inh)
Antidote: Protamine (a basic protein) - neutralizes acidic heparin
Warfarin
Acts as an anticoagulant indirectly
Inhibits the proper synthesis of vitamin K-dependent factors (II, VII, IX and X)
Has a delayed onset action: time required to decrease the plasma levels of preformed
clotting factors
Monitored using protime (PT)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller NurseAdvocate. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.49. You're not tied to anything after your purchase.
