BIOL 4100 EXAM 4 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
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BIOL4100
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BIOL4100
BIOL 4100 EXAM 4 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
Globular (G) actin
Actin monomer with tight binding sites that mediate head-to-tail interactions with two other actin monomers
Filamentous (F) actin
Microfilament formed by polymerization of actin monomers
Barbed (+) end
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biol 4100 exam 4 questions and answers with comple
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BIOL 4100 EXAM 4 QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED
Globular (G) actin
Actin monomer with tight binding sites that mediate head-to-tail interactions with two
other actin monomers
Filamentous (F) actin
Microfilament formed by polymerization of actin monomers
Barbed (+) end
End to which assembly is favored in actin polymerization
Pointed (-) end
End to which assembly is disfavored in actin polymerization
Treadmilling
Phenomenon in which one end of a filament grows in length while the other end shrinks,
resulting in a section of filament seemingly moving across a stratum or the cytosol
T form
Form of actin that is ATP bound
D form
Form of actin that is ADP bound
Nucleation
First stage of actin polymerization in which dimers and trimers form, then monomers are
added to either end
Oligomer instability
, Tendency of actin oligomers to fall apart
Arp2/3
Nucleating complex that is used for initial nucleation of actin filaments and for nucleation
of side branches
Nucleation promotion factor
Activates the Arp2/3 complex to produce branched actin filaments
Formin
Functions as a dimer and interacts with terminal actin subunits
Profilin
Binds actin subunits and speeds elongation by binding to formin monomers and
stimulating ADP to ATP exchange
Tropomodulin
Prevents assembly and disassembly at minus end of actin
Capping protein
Prevents assembly and disassembly at plus end of actin
Cofilin
Stimulates disassembly at minus end of actin
Gelsolin
Severs actin filaments along with cofilin and destrin
Cortex
Dense region of crosslinked actin networks underlying the plasma membrane
Stress fiber
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