The Synapse OSSF II: Questions With Correct Answers
What type of receptors are found on the postsynaptic membrane in chemical
synapses? Right Ans - The postsynaptic membrane contains ionotropic
receptors and metabotropic receptors.
How do neurotransmitters (NTs) affect the postsynaptic cell in chemical
synapse? Right Ans - Neurotransmitters diffuse across the synaptic cleft
and bind with receptors on the postsynaptic cell, initiating a response.
What is the role of voltage-gated Ca²⁺ channels in the presynaptic membrane
of chemical synapse? Right Ans - Voltage-gated Ca²⁺ channels on the
presynaptic membrane are critical for neurotransmitter release into the
synaptic cleft.
How do ionotropic receptors generate fast postsynaptic responses? Right
Ans - Ionotropic receptors are ligand-gated channels that allow ions to flow
across the membrane, leading to fast changes in the postsynaptic membrane
potential, causing EPSPs or IPSPs.
What is the mechanism behind metabotropic receptors and their slower
postsynaptic effects? Right Ans - Metabotropic receptors, such as G-
protein-coupled receptors (GPCRs), activate intracellular second messenger
pathways upon neurotransmitter binding, leading to slower and more
complex responses
What types of postsynaptic effects can be triggered by neurotransmitter
binding? Right Ans - Neurotransmitter binding can trigger excitatory
postsynaptic potentials (EPSPs), inhibitory postsynaptic potentials (IPSPs), or
coordinated intracellular responses.
How does the speed of the postsynaptic response differ between ionotropic
and metabotropic receptors? Right Ans - Ionotropic receptors mediate fast
postsynaptic responses, while metabotropic receptors mediate slower, more
prolonged responses.
Can metabotropic receptors cause EPSPs or IPSPs? Right Ans - Yes,
metabotropic receptors can cause EPSPs, IPSPs, or other coordinated
intracellular responses depending on the signaling pathways activated.
, What is the primary difference between ionotropic and metabotropic
receptors in terms of their structure? Right Ans - Ionotropic receptors are
channel-linked receptors that allow ions to flow directly through the
membrane, whereas metabotropic receptors are G-protein-coupled receptors
that initiate second messenger signaling inside the cell.
Why are neurotransmitters not physically connected to the postsynaptic
membrane? Right Ans - Neurotransmitters are released into the synaptic
cleft, where they diffuse across the gap to bind with receptors on the
postsynaptic cell, without the need for direct physical contact.
What type of synapse uses neurotransmitter? Right Ans - Chemical
What is the primary function of electrical synapses? Right Ans - Electrical
synapses allow ions to pass directly from one cell to another, facilitating
synchronized activity and communication between cells.
How are cells connected in electrical synapses? Right Ans - Cells are
physically connected by gap junctions, which are specialized channels that
allow ion exchange between adjacent cells.
What proteins form gap junctions in electrical synapses? Right Ans -
connexins
What is one major advantage of electrical synapses compared to chemical
synapses? Right Ans - Electrical synapses have no significant synaptic
delay, allowing for faster communication between cells.
In which types of tissues or systems are electrical synapses most commonly
found? Right Ans - Electrical synapses are found in cardiac muscle, smooth
muscle, and certain neural networks.
What type of signals can be transmitted through gap junctions in electrical
synapses? Right Ans - excitatory or inhibitory
Are the signals transmitted through electrical synapses unidirectional or
bidirectional? Right Ans - Signals transmitted through electrical synapses
can be bidirectional, allowing for two-way communication between cells.
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