TEST BANK FOR- FOCUS ON NURSING PHARMACOLOGY 7TH EDITION BY KARCH ISBN: 9781605471860 TEST BANK FOR- FOCUS ON NURSING PHARMACOLOGY 7TH EDITION BY KARCH ISBN: 9781605471860 TEST BANK FOR- FOCUS ON NURSING PHARMACOLOGY 7TH EDITION BY KARCH ISBN: 9781605471860 TEST BANK FOR- FOCUS ON NURSING PHARMACOL...
TEST BANK FOR FOCUS ON NURSING PHARMACOLOGY 7THEDITION BY KARCH
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Material
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Chapter 1: Introduction to Drugs
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Cognitive Level: QP
ApplicationDifficulty:
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Q Moderate
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Integrated Process: Nursing process QP Q P QP
1.A nurse working in radiology administers iodine to a patient who is having a
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computerized axial tomography (CAT) scan. A nurse working on an oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
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14-month-old child as a routine immunization. Which branch of pharmacology
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best describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved QP QP QP QP QP QP QP QP QP QP QP QP
with clinical pharmacology or pharmacotherapeutics, which is a branch of
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pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
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disease. The nurse working in radiology is administering a drug to help diagnose a
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disease. The nurse working on an oncology unit is administering a drug to help treat
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adisease. Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body, and pharmacokinetics QP QP QP QP QP QP QP QP QP
ishow the body acts on the drug.
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Cognitive Level: QP
ComprehensionDifficulty: Easy
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Integrated Process: Nursing process QP Q P QP
2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4
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hours as needed for pain for a motor vehicle accident victim. The nurse is aware
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thatthere is a high abuse potential for this drug; therefore, morphine is categorized as
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a:
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A) Schedule I drug QP QP
B) Schedule II drug QP QP
C) Schedule III drug QP QP
D) Schedule IV drug QP QP
Ans: B
Response:
Narcotics such as morphine are considered schedule II drugs because of the high
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abuse potential with severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser abuse
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potential than schedule II drugs and an accepted medical use. Schedule IV drugs
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havelow abuse potential and limited dependence liability.
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Cognitive Level: QP
ComprehensionDifficulty: Easy
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Integrated Process: Communication and documentation QP Q P QP QP
3.A nurse working for a drug company is involved in phase III drug evaluation
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studies.Which of the following might the nurse be responsible for during this stage
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of drug development?
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, Chapter 1: Introduction to QP QP QP
Drugs
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A) Working with animals who are given experimental drugs QP QP QP QP QP QP QP
B) Monitoring drug effects in patients who are selected to participate in a QP QP QP QP QP QP QP QP QP QP QP
study,who have the disease that the drug is meant to treat
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C) Collecting records of symptoms that participants experience while taking QP QP QP QP QP QP QP QP
adrug and determining whether they are caused by the disease or the drug
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D) Informing healthy, young volunteer participants of possible risks that QP QP QP QP QP QP QP QP
couldoccur from taking an experimental drug
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Ans: C
Response:
Phase III studies involve use of a drug in a vast clinical market where patients are
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asked to record any symptoms they experience while taking the drugs. Nurses may
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beresponsible for helping collect and analyze the information to be shared with the
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Food and Drug Administration (FDA). Use of animals in drug testing is done in the
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preclinical trials. A select group of patients who are involved in phase II studies
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participate in studies where the participants have the disease the drug is intended to
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treat. These patients are monitored closely for drug effects. Phase I studies involve
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healthy human volunteers who are usually paid for their participation. Nurses may
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observe for adverse effects and toxicity.
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Cognitive Level: QP
ComprehensionDifficulty:
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Moderate
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Integrated Process: Nursing Process QP Q P QP
4.Which of the following concepts is considered when generic drugs are substituted
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forbrand-name drugs?
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A) Bioavailability
B) Critical concentration QP
C) Distribution
D) Half-life
Ans: A
Response:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation QP QP QP QP QP QP QP QP QP QP QP QP QP QP
and is available to act on body cells. Binders used in a generic drug may not be the
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same as those used in the brand-name drug. Therefore, the way the body breaks
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downand uses the drug may differ, which may eliminate a substitution. Critical
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concentration is the amount of a drug that is needed to cause a therapeutic effect.
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Distribution is the phase of pharmacokinetics that involves the movement of a drugQP QP QP QP QP QP QP QP QP QP QP QP
tothe body's tissues. A drug's half-life is the time it takes for the amount of drug to
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decrease to one-half of the peak level.
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Cognitive Level: QP
AnalysisDifficulty: Difficult
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Integrated Process: Teaching/learning QP Q P
5.A nurse is teaching her patient about the use of over-the-counter (OTC) drugs.
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QPWhichof the following statements best informs the patient about their safe use?
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A) ―OTC drugs are products that are available without prescription for self-
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treatment of minor complaints.‖
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B) ―OTC drugs are considered medications and should be reported on a drug QP QP QP QP QP QP QP QP QP QP QP
history.‖ QP
, Chapter 1: Introduction to
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Drugs
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C) ―OTC drugs were approved as prescription drugs but later were found to be
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safe without the need for a prescription.‖
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D) ―OTC drugs need to be taken with caution. They can mask the signs and
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symptoms of an underlying disease and interfere with prescription drug
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therapy.‖ QP
Ans: D
Response:
OTC drugs are considered medications and should be reported. OTC drugs are
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available without a prescription, although some were first approved as prescription
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drugs. The most important teaching should relate to their safe use and that OTC
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drugscan mask symptoms of disease and interfere with prescribed drugs.
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Cognitive Level: QP
KnowledgeDifficulty: Easy
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Integrated Process: Nursing Process QP Q P QP
6.Which of the following legislative acts allowed the Food and Drug
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Administration(FDA) to tighten control over the quality of drugs and required that
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safety and efficacy standards be established?
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A) Pure Food and Drug Act of 1906 QP QP QP QP QP QP
B) Federal Food, Drug, and Cosmetic Act of 1938 QP QP QP QP QP QP QP
C) Durham HumphreyAmendment of 1951 QP Q
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D) Kefauver-Harris Act of 1962 QP QP QP
Ans: D
Response:
The Kefauver-Harris Act was the result of the use of the 1960s drug thalidomide
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(Thalomid). The public concern led to the legislation that gave the FDA regulatory
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control over testing and evaluating of drugs and allowed it to set standards for
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efficacy and safety. The Pure Food and Drug Act required labeling to eliminate
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falseclaims. The Federal Food, Drug, and Cosmetic Act gave the FDA the power to
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enforce standards for testing drug toxicity and monitoring labeling. The Durham-
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HumphreyAmendment enforced prescriptions for distribution.
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Cognitive Level: QP
ApplicationDifficulty:
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Moderate
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Integrated Process: Teaching/learning QP Q P
7.A nurse is instructing a pregnant patient concerning the potential risk to her
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fetusfrom a pregnancy category B drug. The nurse would inform the patient that:
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A) ―Adequate studies in pregnant women have demonstrated there is no risk to the QP QP QP QP QP QP QP QP QP QP QP QP
fetus.‖ QP
B) ―Animal studies have not demonstrated a risk to the fetus but there have been QP QP QP QP QP QP QP QP QP QP QP QP QP
no adequate studies in pregnant women.‖
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C) ―Animal studies have shown an adverse effect on the fetus but there are no QP QP QP QP QP QP QP QP QP QP QP QP QP
adequate studies in pregnant women.‖
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D) ―There is evidence of human fetal risk but the potential benefits from use of the
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drug may be acceptable despite potential risks.‖
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Ans: B
Response:
Category B indicates that animal studies have not demonstrated a risk to the fetus but
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