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Exam (elaborations)

APEA- Psych Pharm Final Exam.

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APEA- Psych Pharm Final Exam. Bupropion (Wellbutrin), used in the treatment of depression, should NOT be administered to a patient with: alcoholism. attention deficit disorder. hypertension. seizure disorder. - CORRECT ANSWER seizure disorder. First-generation antipsychotics (e.g., halope...

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  • December 7, 2024
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  • 2024/2025
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NURSEMISH
APEA- Psych Pharm Final Exam.
Bupropion (Wellbutrin), used in the treatment of depression, should NOT be administered to a patient
with:

alcoholism.

attention deficit disorder.

hypertension.

seizure disorder. - CORRECT ANSWER seizure disorder.



First-generation antipsychotics (e.g., haloperidol [Haldol]) are associated with side effects including:

sedation.

tardive dyskinesia.

weight gain.

weight loss. - CORRECT ANSWER tardive dyskinesia.



If methylphenidate is contraindicated, which of the following medications is recommended for
treatment of ADHD in an adult?

Bupropion (Wellbutrin)

Clonazepam (Klonopin)

Fluoxetine (Prozac)

Phenelzine (Nardil) - CORRECT ANSWER Bupropion (Wellbutrin)



Therapeutic drug levels and predictability of clinical response are difficult to determine in first-
generation antipsychotics (e.g., haloperidol [Haldol]) because they:

are poorly absorbed in the intestines, hydrophilic and highly protein bound.

, are highly bioavailable and poorly protein bound.

have a decreased first pass effect, are hydrophilic and poorly protein bound.

have variable bioavailability, are lipophilic and highly protein bound. - CORRECT ANSWER have variable
bioavailability, are lipophilic and highly protein bound.



Guanfacine (Intuniv), used in the treatment of attention deficit disorder, is classified as a(n):

alpha-2-adrenergic agonist.

selective norepinephrine reuptake inhibitor.

sympathomimetic/stimulant.

tricyclic antidepressant. - CORRECT ANSWER alpha-2-adrenergic agonist.



Suvorexant (Belsomra), used in the treatment of insomnia, induces sleep by:

activating melatonin receptors.

blocking the signals of orexin chemicals in the hypothalamus.

increasing the catabolism of tryptophan.

raising the levels of gamma-aminobutyric acid (GABA). - CORRECT ANSWER blocking the signals of orexin
chemicals in the hypothalamus.



The mechanism of action of second-generation antipsychotic medications such as aripiprazole (Abilify)
does NOT include:

5-HT2A receptor blockade.

dopamine D2 receptor blockade.

serotonin reuptake stimulation.

enhanced dopamine release. - CORRECT ANSWER serotonin reuptake stimulation.



After initiation or increase in dose of a selective serotonin receptor inhibitor (SSRI) such as escitalopram
(Lexapro), the patient should be monitored for:

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