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Summary - Cytologie en histologie

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Samenvatting van 1 pagina's voor het vak Cytologie en histologie aan de UGent (sv histo)

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  • December 8, 2024
  • 1
  • 2024/2025
  • Summary
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Hoofdstuk 4: gewrichtskraakbeen

Vervolg. Vanuit hoofdstuk 2: soorten bindweefsels
3. Steunweefsel
3.2. Kraakbeen
= een primair weefsel, in de bovenste laag, specifiek soort kraakbeen

- Vezelrichting
o Specifieke organisatie
 Op bot: verticaal
 Op opp.: horizontaal, evenwijdig met opp.
- Doel
 Wrijving op 2 oppervlakten verminderen
 Drukkrachten opvangen
- Beweging van het been
o op been staan/ lopen
 gewrichtskraakbeen onder druk
 koolhydarten structuur aan uiteinden bij elkaar
 water en ionen uitpersen
 vocht in synovium zuigen
o been in rust
 water aanzuigen  compartimenten vullen
 vocht uit synovium zuigen
 koolhydarten structuur terug uit elkaar
- Osteoartrose
o Geen kraakbeen? Snelle slijtage  osteoartrose = slijtage
o door veroudering: fysieke activiteit is laag
 osteocyten worden aangetast
 slechtere opbouw en afbraak
 niet meer (volledig) hersteld
o door sporten: fysieke activiteit is hoog
 = belastbaarheid is laag, belasting is hoog
 Oplossing: osteocyten worden geactiveerd
o Kraakbeenletsel (scheur)
 scheur opvullen met een matrix
 matrix = chondrocyten en chondroblasten  worden gematched
 scheuren als gevolg van overbelasting of onderbelasting
 slijten als gevolg van normale belasting
- tussenlaag:
o overgangslaag tussen bovenste en onderste vezel

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