Tuberculosis Questions and Answers
with Verified Solutions
William Parish, a 45-year-old male, presents with a persistent cough, weight loss, night sweats,
and a history of close contact with a family member who had tuberculosis (TB). His chest X-ray
shows infiltrates in the upper lobes. A sputum smear for acid-fast bacilli (AFB) is positive. What
is the most likely diagnosis for William?
✔✔Active pulmonary tuberculosis
Pneumonia
Chronic bronchitis
Lung cancer
What is the next step in managing William's case after diagnosing active tuberculosis (TB)?
✔✔Initiate a 4-drug TB regimen (isoniazid, rifampin, pyrazinamide, and ethambutol)
Prescribe antibiotics for bacterial pneumonia
Recommend a chest physiotherapy program
Perform a lung biopsy
Considering William’s positive sputum smear for AFB, what is the most appropriate isolation
precaution for him in the hospital?
1
,✔✔Airborne isolation
Contact isolation
Standard precautions
Droplet isolation
What is the significance of William’s close contact with a family member who had TB in the
context of his diagnosis?
✔✔He is at high risk for latent tuberculosis infection (LTBI) or reactivation of TB
He likely contracted the infection due to poor hygiene
It indicates he has a higher risk of pneumonia
It suggests he has a viral respiratory infection
Which diagnostic test would be most useful to confirm rifampin resistance in William’s TB
case?
✔✔GeneXpert MTB/RIF assay
Chest X-ray
Interferon-gamma release assay (IGRA)
Tuberculin skin test
2
, What is the recommended duration of treatment for William, who has active TB and is expected
to be drug-susceptible?
✔✔6-9 months of antibiotics
1-3 months of antibiotics
12 months of antibiotics
6 months of steroids
What is the main goal of TB treatment for William?
✔✔To eliminate Mycobacterium tuberculosis and prevent transmission
To reduce the inflammation in the lungs
To manage his weight loss
To relieve his night sweats
Given William’s symptoms, which of the following is a common symptom of active
tuberculosis?
✔✔Night sweats
Increased appetite
3
with Verified Solutions
William Parish, a 45-year-old male, presents with a persistent cough, weight loss, night sweats,
and a history of close contact with a family member who had tuberculosis (TB). His chest X-ray
shows infiltrates in the upper lobes. A sputum smear for acid-fast bacilli (AFB) is positive. What
is the most likely diagnosis for William?
✔✔Active pulmonary tuberculosis
Pneumonia
Chronic bronchitis
Lung cancer
What is the next step in managing William's case after diagnosing active tuberculosis (TB)?
✔✔Initiate a 4-drug TB regimen (isoniazid, rifampin, pyrazinamide, and ethambutol)
Prescribe antibiotics for bacterial pneumonia
Recommend a chest physiotherapy program
Perform a lung biopsy
Considering William’s positive sputum smear for AFB, what is the most appropriate isolation
precaution for him in the hospital?
1
,✔✔Airborne isolation
Contact isolation
Standard precautions
Droplet isolation
What is the significance of William’s close contact with a family member who had TB in the
context of his diagnosis?
✔✔He is at high risk for latent tuberculosis infection (LTBI) or reactivation of TB
He likely contracted the infection due to poor hygiene
It indicates he has a higher risk of pneumonia
It suggests he has a viral respiratory infection
Which diagnostic test would be most useful to confirm rifampin resistance in William’s TB
case?
✔✔GeneXpert MTB/RIF assay
Chest X-ray
Interferon-gamma release assay (IGRA)
Tuberculin skin test
2
, What is the recommended duration of treatment for William, who has active TB and is expected
to be drug-susceptible?
✔✔6-9 months of antibiotics
1-3 months of antibiotics
12 months of antibiotics
6 months of steroids
What is the main goal of TB treatment for William?
✔✔To eliminate Mycobacterium tuberculosis and prevent transmission
To reduce the inflammation in the lungs
To manage his weight loss
To relieve his night sweats
Given William’s symptoms, which of the following is a common symptom of active
tuberculosis?
✔✔Night sweats
Increased appetite
3
