Lehne's Pharmacology for Nursing Care 12th Edition
COMPLETE TEST BANK FOR
Lehne's Pharmacology for Nursing Care 12th Edition
by Jacqueline Rosenjack Burchum DNSc FNP-BC CNE (2024 –
2025)|| VERIFIED CHAPTERS 1 – 113 COMPLETE NEWEST
VERSION, GRADE A+ TEST BANK FOR LEHNE’S
PHARMACOLOGY FOR NURSING CARE 12TH EDITION
12TH EDITION
, Lehne's Pharmacology for Nursing Care 12th Edition
Table of Contents
Unit I: Introduction ....................................................................................................................................... 7
Chapter 1: Orientation To Pharmacology ................................................................................................. 7
Chapter 2: Application Of Pharmacology In Nursing Practice ................................................................ 10
Chapter 3: Drug Regulation, Development, Names, And Information ................................................... 17
Unit Ii: Basic Principles Of Pharmacology ................................................................................................... 20
Chapter 4: Pharmacokinetics .................................................................................................................. 20
Chapter 5: Pharmacodynamics ............................................................................................................... 27
Chapter 6: Drug Interactions .................................................................................................................. 31
Chapter 7: Adverse Drug Reactions And Medication Errors ................................................................... 38
Chapter 8: Individual Variation In Drug Responses ................................................................................ 45
Chapter 9: Genetic And Genomic Considerations .................................................................................. 51
Chapter 10: Introduction To Immunomodulators ................................................................................. 54
Unit Iii: Drug Therapy Across The Life Span ................................................................................................ 57
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding......................................................... 57
Chapter 12: Drug Therapy In Pediatric Patients ..................................................................................... 63
Chapter 13: Drug Therapy In Older Adults.............................................................................................. 68
Unit Iv: Peripheral Nervous System Drugs .................................................................................................. 79
Chapter 14: Basic Principles Of Neuropharmacology ............................................................................ 79
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................... 83
Chapter 16: Muscarinic Agonists ........................................................................................................... 88
Chapter 17: Muscarinic Antagonists ..................................................................................................... 91
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis .......................................... 96
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ....................................................... 102
Chapter 20: Adrenergic Agonists .......................................................................................................... 108
Chapter 21: Adrenergic Antagonists ..................................................................................................... 115
Chapter 22: Indirect-Acting Antiadrenergic Agents .............................................................................. 124
Unit V: Central Nervous System Drugs ..................................................................................................... 129
Chapter 23: Introduction To Central Nervous System Pharmacology .................................................. 130
Chapter 24: Drugs For Parkinson’s Disease .......................................................................................... 133
Chapter 25: Drugs For Alzheimer Disease............................................................................................. 141
Chapter 26: Drugs For Multiple Sclerosis.............................................................................................. 146
Chapter 27: Drugs For Seizure Disorders .............................................................................................. 153
, Lehne's Pharmacology for Nursing Care 12th Edition
Chapter 28: Drugs For Muscle Spasm And Spasticity ........................................................................... 163
Chapter 29: Local Anesthetics............................................................................................................... 167
Chapter 30: General Anesthetics .......................................................................................................... 174
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics ....... 181
Chapter 32: Pain Management In Patients With Cancer ...................................................................... 189
Chapter 33: Drugs For Headache .......................................................................................................... 198
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ..................................................... 204
Chapter 35: Antidepressants ................................................................................................................ 212
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 222
Chapter 37: Sedative-Hypnotic Drugs ................................................................................................... 228
Chapter 38: Management Of Anxiety Disorders ................................................................................... 238
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ........ 242
Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................. 249
Chapter 41: Substance Use Disorders Ii: Alcohol .................................................................................. 253
Chapter 42: Substanceuse Disorders Iii: Nicotine ................................................................................. 263
Chapter 43: Substance Use Disorders Iv: Major Drugs Of Abuse Other Than Alcohol And Nicotine ... 268
Unit Vi: Drugs That Affect Fluid And Electrolyte Balance ......................................................................... 278
Chapter 44: Diuretics ............................................................................................................................ 278
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ........................................ 285
Unit Vii: Drugs That Affect The Heart, Blood Vessels, And Blood ............................................................. 292
Chapter 46: Review Of Hemodynamics ................................................................................................ 292
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ......................................... 296
Chapter 48: Calcium Channel Blockers ................................................................................................. 303
Chapter 49: Vasodilators....................................................................................................................... 307
Chapter 50: Drugs For Hypertension .................................................................................................... 313
Chapter 51: Drugs For Heart Failure ..................................................................................................... 323
Chapter 52: Antidysrhythmic Drugs ...................................................................................................... 335
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ...................................... 346
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 355
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ...................................................... 364
Chapter 56: Management Of St-Elevation Myocardial Infarction ........................................................ 374
Chapter 57: Drugs For Hemophilia ....................................................................................................... 380
Chapter 58: Drugs For Deficiency Anemias........................................................................................... 386
, Lehne's Pharmacology for Nursing Care 12th Edition
Chapter 59: Hematopoietic Agents....................................................................................................... 394
Unit Viii: Drugs For Endocrine Disorders................................................................................................... 400
Chapter 60: Drugs For Diabetes Mellitus .............................................................................................. 400
Chapter 61: Drugs For Thyroid Disorders ............................................................................................. 408
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function................................................... 416
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ...................................................................... 423
Unit Ix: Reproductive Health ..................................................................................................................... 429
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications ..... 429
Chapter 65: Birth Control ...................................................................................................................... 435
Chapter 66: Drug Therapy Of Infertility ................................................................................................ 443
Chapter 67: Drugs That Affect Uterine Function .................................................................................. 449
Chapter 68: Androgens ......................................................................................................................... 455
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ................................... 462
Chapter 70: Transgender Health ........................................................................................................... 468
Unit X: Anti-Inflammatory, Antiallergic, And Immunologic Drugs ............................................................ 475
Chapter 71: Review Of The Immune System ........................................................................................ 475
Chapter 72: Childhood Immunization ................................................................................................... 481
Chapter 73: Immunosuppressants ........................................................................................................ 490
Chapter 74: Antihistamines .................................................................................................................. 497
Chapter 75: Cyclooxygenase Inhibitors: Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
.............................................................................................................................................................. 505
Chapter 76: Glucocorticoids In Nonendocrine Disorders ..................................................................... 514
Unit Xi: Drugs For Bone And Joint Disorders ............................................................................................ 522
Chapter 77: Drug Therapy Of Rheumatoid Arthritis ............................................................................. 522
Chapter 78: Drug Therapy Of Gout ....................................................................................................... 526
Chapter 79: Drugs Affecting Calcium Levels And Bone Mineralization ................................................ 531
Unit Xii: Respiratory Tract Drugs ............................................................................................................... 540
Chapter 80: Drugs For Asthma And Chronic Obstructive Pulmonary Disease...................................... 540
Chapter 81: Drugs For Allergic Rhinitis, Cough, And Colds ................................................................... 550
Unit Xiii: Gastrointestinal Drugs ................................................................................................................ 556
Chapter 82: Drugs For Peptic Ulcer Disease ......................................................................................... 557
Chapter 83: Laxatives ............................................................................................................................ 563
Chapter 84: Other Gastrointestinal Drugs ............................................................................................ 570
, Lehne's Pharmacology for Nursing Care 12th Edition
Unit Xiv: Nutrition And Complimentary Therapy ...................................................................................... 581
Chapter 85: Vitamins ............................................................................................................................ 581
Chapter 86: Drugs For Weight Loss....................................................................................................... 590
Chapter 87: Complementary And Alternative Therapy ....................................................................... 598
Unit Xv: Therapy Of Infectious Diseases ................................................................................................... 611
Chapter 88: Basic Principles Of Antimicrobial Therapy ........................................................................ 611
Chapter 89: Drugs That Weaken The Bacterial Cell Wall I: Penicillins .................................................. 619
Chapter 90: Drugs That Weaken The Bacterial Cell Wall Ii: Other Drugs ............................................. 627
Chapter 91: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others ... 634
Chapter 92: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis......................................... 645
Chapter 93: Sulfonamides And Trimethoprim ...................................................................................... 654
Chapter 94: Drug Therapy For Urinary Tract Infections ....................................................................... 661
Chapter 95: Antimycobacterial Agents: Drugs For Tuberculosis .......................................................... 669
Chapter 96: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole, Daptomycin,
Rifampin, Rifaximin, And Fidaxomicin .................................................................................................. 680
Chapter 97: Antifungal Agents .............................................................................................................. 685
Chapter 98: Antiviral Agents I: Drugs For Non-Hiv Viral Infections ...................................................... 697
Chapter 99: Antiviral Agents Ii: Drugs For Hiv Infection And Related Opportunistic Infections .......... 705
Chapter 100: Drug Therapy For Sexually Transmitted Infections ......................................................... 713
Chapter 101: Antiseptics And Disinfectants ......................................................................................... 719
Unit Xvi: Chemotherapy Of Parasitic Diseases.......................................................................................... 725
Chapter 102: Anthelmintics .................................................................................................................. 725
Chapter 103: Antiprotozoal Drugs I: Antimalarial Agents .................................................................... 731
Chapter 104: Antiprotozoal Drugs Ii: Miscellaneous Agents ................................................................ 737
Chapter 105: Ectoparasiticides ............................................................................................................. 741
Unit Xvii: Cancer Chemotherapy ............................................................................................................... 748
Chapter 106: Basic Principles Of Cancer Treatment ............................................................................. 748
Chapter 107: Anticancer Drugs I: Cytotoxic Agents .............................................................................. 757
Chapter 108: Anticancer Drugs Ii: Hormonal Agents, Targeted Drugs, And Other Noncytotoxic
Anticancer Drugs ................................................................................................................................... 766
Unit Xviii: Miscellaneous Drugs And Therapies ........................................................................................ 772
Chapter 109: Drugs For The Eye Conditions And Diseases ................................................................... 772
Chapter 110: Drugs For Skin Conditions ............................................................................................... 780
, Lehne's Pharmacology for Nursing Care 12th Edition
Chapter 111: Drugs For Ear Conditions................................................................................................. 791
Unit Xix: Toxicology ................................................................................................................................... 801
Chapter 112: Management Of Poisoning ............................................................................................. 801
Chapter 113: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ............................ 807
, Lehne's Pharmacology for Nursing Care 12th Edition
Unit I: Introduction
Chapter 1: Orientation To Pharmacology
Multiple Choice
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This, The
Nurse Will Rely On Knowledge Of:
A. Clinical Pharmacology.
B. Drug Efficacy.
C. Pharmacokinetics.
D. Pharmacotherapeutics.
CORRECT ANS>> D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent Conditions.
Clinical Pharmacology Is Concerned With All Aspects Of Drug–Human Interactions. Drug Efficacy
Measures The Extent To Which A Given Drug Causes An Intended Effect.
Pharmacokinetics Is The Study Of The Impact Of The Body On A Drug.
Dif: Cognitive Level: ComprehensionRef: Four Basic Terms Top: Nursing Process: Implementation
Msc: Nclex Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral Therapies
2. What Does It Mean When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
CORRECT ANS>> C
, Lehne's Pharmacology for Nursing Care 12th Edition
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More Likely To
Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other Attributes Listed, But
Those Properties Are Independent Of Ease Of Administration.
Dif: Cognitive Level: Comprehension
Ref: Additional Properties Of An Ideal Drug: Ease Of Administration Top: Nursing Process: Assessment
Msc: Nclex Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral Therapies
3. A Patient Tells The Nurse That He Was Told By The Prescriber That The Analgesic He Is Taking Is
Very Effective. Which Statement By The Patient Demonstrates An Understanding Of The Drug’s
Effectiveness?
A. “I Don’t Have To Worry About Toxicity, Since It Takes A Large Amount Of This Drug To Cause An
Overdose.”
B. “It Has No Side Effects And Doesn’t Interact With Other Drugs.”
C. “I Only Have To Take It Every 12 Hours.”
D. “It Might Make Me Sleepy, And It Lessens Pain For Several Hours At A Time.”
CORRECT ANS>> D
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects. Because No
Drug Is Completely Safe, The Level Of Toxicity Does Not Determine Effectiveness. All Drugs Have Side
Effects And Many React With Other Substances; These Do Not Affect The Drug’s Effectiveness. Ease Of
Administration Is Independent Of A Drug’s Effectiveness.
Dif: Cognitive Level: ComprehensionRef: Properties Of An Ideal Drug Top: Nursing Process:
Evaluation
Msc: Nclex Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral Therapies
Multiple Response
1. What Are The Properties Of An Ideal Drug? (Select All That Apply.)
A. Irreversible Action
B. Predictability
, Lehne's Pharmacology for Nursing Care 12th Edition
C. Ease Of Administration
D. Chemical Stability
E. A Simple Trade Name
CORRECT ANS>> B, C, D
In Addition To Predictability, Ease Of Administration, And Chemical Stability, Other Properties Include A
Reversible Action So That Any Harm The Drug May Cause Can Be Undone And A Simple Generic Name,
Because Generic Names Are Usually Complex And Difficult To Remember And Pronounce.
Dif: Cognitive Level: Comprehension
Ref: Properties Of An Ideal Drug | Additional Properties Of An Ideal Drug Top: Nursing Process:
Assessment
Msc: Nclex Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral Therapies
2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate How
Individual Patient Variability Might Affect The Patient’s Response To The Medication? (Select All That
Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
D. Patient’s Age
E. Patient’s Diagnosis
CORRECT ANS>> C, D, E
The Family Medical History Can Indicate Genetic Factors That May Affect A Patient’s Response To A
Medication. Patients Of Different Ages Can Respond Differently To Medications. The Patient’s Illness Can
Affect How Drugs Are Metabolized. The Chemical Stability Of The Medication And The Ease Of
Administration Are Properties Of Drugs.
Dif: Cognitive Level: Analysis Ref: Sources Of Individual Variation Top: Nursing Process:
Implementation
Msc: Nclex Client Needs Category: Physiologic Integrity: Reduction Of Risk Potential
