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Definition
*A) 3′ TTACCGAAT 5′
B) 5′ TAAGCCATT 3′
C) 3′ AATGGCTTA 5′
D) 5′ AATGGCTTA 3′
E) 5′ TTACCGAAT 3′
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A chromosome contains the following gene order:
ABCD • EFGH
Which of the following rearrangements represents a pericentric inversion?
Which of the following tends to be associated with genes whose transcription is
regulated (e.g., not constitutively expressed)?
A patient comes in to the clinic with a series of symptoms that do not match a
specific disease. The doctor decides to send their DNA sample for Whole Genome
NGS sequencing. After sequencing the bioinformatics researcher receives the
sequence data. What are the next steps in searching for a candidate mutation that is
causing the patient's symptoms?
, A portion of one strand of DNA has the sequence 5′ AATGGCTTA 3′. If this
strand is used as a template for DNA replication, which of the following
correctly depicts the sequence of the newly synthesized strand in the
direction in which it will be synthesized?
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2 of 140
Term
The brain mass in a population of mice has a phenotypic variance of
0.56 g2 and an environmental variance of 0.14 g2. What is the broad
sense heritability (H2)?
The brain mass in a population of mice has a phenotypic variance of
0.68 g2 and an
environmental variance of 0.23 g2. What is the broad sense heritability
(H2)?
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A) 0.25
B) 0.42
*C) 0.75
D) 1.54
E) The broad sense heritability cannot be calculated with the data provided
, A) 0.25
*B) 0.66
C) 0.71
D) 1
E) The broad sense heritability cannot be calculated with the data provided
a) Allele A1 co-segregates with the disease causing mutation.
b) Allele A2 co-segregates with the disease causing mutation.
*c) Allele A3 co-segregates with the disease causing mutation.
d) Allele A4 co-segregates with the disease causing mutation.
e) Gene A is not genetically linked to the disease causing mutation.
A. 0.40 A1, 0.60 A2 B. 0.50 A1, 0.50 A2 *C. 0.60 A1, 0.40 A2 D. 0.80 A1, 0.20 A2 E. All A1
*a) 5.08
b) 0.34
c) 121.9
d) 0.05
*a) larger than 0.5 - conclude that differences are caused by chance
b) larger than 0.5 - conclude that differences are significant and not by chance
c) smaller than the 0.05 cutoff for significance
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