Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? - ** VERIFIED ANSWERS **✔✔Dolophine
What type of opioid receptor agonist is Methadone? - ** VERIFIED ANSWERS **✔✔Long-
acting full agonist at the mu receptor
How often is Methadone dosed? - ** VERIFIED ANSWERS **✔✔Once daily
In what type of programs is Methadone use restricted? - ** VERIFIED ANSWERS
**✔✔Federally licensed substance abuse treatment programs
What should be monitored when using Methadone? - ** VERIFIED ANSWERS **✔✔QTC
prolongation
What is Buprenorphine (Buprenex, Sublocade)? - ** VERIFIED ANSWERS **✔✔Partial
Opioid receptor agonist
What is the function of Buprenorphine/Naloxone (Suboxone)? - ** VERIFIED ANSWERS
**✔✔Opioid antagonist
,What effect does Buprenorphine have on cravings? - ** VERIFIED ANSWERS
**✔✔Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? - ** VERIFIED
ANSWERS **✔✔Waiver needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? - **
VERIFIED ANSWERS **✔✔Can precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? - ** VERIFIED
ANSWERS **✔✔It will displace any residual opioids from the mu receptors
What is the route of administration for Suboxone? - ** VERIFIED ANSWERS
**✔✔Sublingual preparation
In what situation can Suboxone be used in managing pain? - ** VERIFIED ANSWERS
**✔✔Opioid Use disorder w/ comorbid pain
What type of antagonist is Naltrexone? - ** VERIFIED ANSWERS **✔✔Competitive opioid
antagonist
What can happen if Naltrexone is used within 7 days of heroin use? - ** VERIFIED
ANSWERS **✔✔Precipitate withdrawal
How is Naltrexone available for use? - ** VERIFIED ANSWERS **✔✔Orally or monthly
depot injection
When is Naltrexone considered the treatment of choice? - ** VERIFIED ANSWERS
**✔✔For highly motivated patients
, What is a potential risk associated with Naltrexone use? - ** VERIFIED ANSWERS
**✔✔Risk for LFT elevation
Naltrexone - ** VERIFIED ANSWERS **✔✔Available PO (Revia) Available IM (Vivitrol)
What are the common symptoms of opioid overdose? - ** VERIFIED ANSWERS
**✔✔Miosis, Hypotension, Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? - ** VERIFIED ANSWERS **✔✔Naloxone
What are the symptoms of opioid withdrawal? - ** VERIFIED ANSWERS **✔✔Anxiety,
Lacrimation, Muscle aches, Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? - ** VERIFIED ANSWERS
**✔✔Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing withdrawal
symptoms towards the end of the taper? - ** VERIFIED ANSWERS **✔✔Buprenorphine
(compared to methadone)
What are some symptoms of cocaine use? - ** VERIFIED ANSWERS **✔✔Auditory
hallucinations, agitation, violent behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? - ** VERIFIED ANSWERS
**✔✔It is used to treat agitation and muscle twitching associated with cocaine use
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