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Teratogens for the Genetic Counseling Board Exam Questions and Answers 100% Pass
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Teratogens for the Genetic Counseling Board Exam Questions and Answers 100% Pass ACE inhibitors - ANSWER -"the only anti-hypertensive medications associated with structural defects, Renal tubular dysplasia -> oligohydramnios, Potter's sequence, and pulmonary hypoplasia IUGR Hypocalvaria man...

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  • December 19, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • teratogens for the genetic counseling board exam q

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  • ABGC
  • ABGC

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GraceAmelia

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Teratogens for the Genetic Counseling Board Exam
Questions and Answers 100% Pass


ACE inhibitors - ANSWER ✔✔-"the only anti-hypertensive medications associated with structural

defects, Renal tubular dysplasia -> oligohydramnios, Potter's sequence, and pulmonary hypoplasia


IUGR


Hypocalvaria manifested by large anterior fontanel, vasodilation, severe fetal hypotension,

anuria/oligura"


Alcohol - ANSWER ✔✔-"Growth restriction


CNS involvement, (intelligence & behavior)


Characteristic facial features such as ptosis, short palpebral fissures, smooth philtrum and thin upper

vermilion, microcephaly, flat nasal bridge"


Aminopterin - ANSWER ✔✔-(50%) IUGR, Short stature, delayed calvarial ossification, craniosynostosis,

hydrocephalus, abnormal auricles, ocular hypertelorism, microignathia, Cleft Palate, limb & digital

anomalies, NTDs


Amphetamines - ANSWER ✔✔-heart defects and CL in some mice


Anticonvulsants - ANSWER ✔✔-"6-15% risk for major malformations


Hypertelorism


Broad depressed nasal bridge


Short nose with anteverted nares




Created by Grace Amelia © 2025, All Rights Reserved.

, 2|Page


"Cupid's bow" lip


Fingernail hypoplasia


Meningomyelocele


Oral clefts


Congenital heart defects


Limb defects


Developmental delay, most significantly with valproic acid"


Aspirin - ANSWER ✔✔-inc SAb risk when exposed around conception, avoid in late pregnancy due to

concerns for premature constriction of ductus arteriosus & bleeding abnormalities


Benzodiazepines - ANSWER ✔✔-"Clefting?


neonatal adaptation syndrome"


Carbamazepine (Tegretol) - ANSWER ✔✔-Spina Bifida (1%), craniofacial anomalies, dev delay?


Cigarettes - ANSWER ✔✔-Infertility, ectopic pregnancy, miscarraige, placental abruption, placental

previa, fetal growth restriction (dose dependant), preterm delivery, SIDS, orofacial clefts, abnormal

placentation, decreased childhood pulmonary fxn, ADHD, food allergies


Cocaine - ANSWER ✔✔-Premature labor/birth, abruption, uterine rupture, cerebral infarction (stroke),

brain disruptions, Sab, behavioural abnormalities


Codeine - ANSWER ✔✔-"Mothers ultrarapid metabolizers of cytochrome P450 2D6-> Newborn exposed

to toxic doses of morphine


(1/100-28/100 in population)


excessive sleepiness, feeding and respiratory difficulties"



Created by Grace Amelia © 2025, All Rights Reserved.

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