"Systemic Lupus Erythematosus (SLE): Pathophysiology, Diagnosis, Treatment, and Nursing Care"
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MED-SURG
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MED-SURG
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Study Guide for Lewis\' Medical-Surgical Nursing - E-Book
This document provides an in-depth review of Systemic Lupus Erythematosus (SLE), focusing on its pathophysiology, clinical manifestations, diagnostic criteria, and treatment options. It explains the autoimmune nature of SLE, common symptoms such as the butterfly rash, joint pain, and lupus nephriti...
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Systemic Lupus Erythematosus
(SLE; Lupus)
An autoimmune disease in which the immune system attac
own tissues, causing widespread inflammation and tissue dama
the affected organs.
* joints, skin, brain, lungs, kidneys, heart, and blood vessels.
CAUSES:*the main cause is still unknown.
Common in women especially African, Latina, & Asian
Hormone – Estrogen which increases during the reproductive
enhances the activity of B cells, autoantibodies in lupus.
Also affects T cells, promotes a pro-inflammatory immune re
, Systemic Lupus Erythematosus
(SLE; Lupus)
Genetics – have harder to clear apoptotic bodies and control
inflammation
Environmental factors – triggers like UV light, infections,
smoking, medications, and stress.
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