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Samenvatting 24-24 Bacteriologie deel 2 : antibiotica
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Samenvatting van deel 2 : antibiotica het vak bacteriologie en virologie Gegeven in het 3de jaar MLT
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BACTERIOLOGIE EN SEROLOGIEDEEL 2 : ANTIBIOTICA
Lector. Vanhentenrijk Chris
Academiejaar
2024 - 2025
,IN HOUDSOPGAVE
1. Inleiding ................................................................................................................................................................ 3
1.1 Antibiotica....................................................................................................................................................... 3
1.2 Bacterie........................................................................................................................................................... 3
1.3 Werkingsmechanismen .................................................................................................................................. 3
1.4 Werkingsspectrum.......................................................................................................................................... 4
1.5 Resistentie ...................................................................................................................................................... 4
2. -lactamantibiotica............................................................................................................................................... 6
2.1 Werkingsmechanisme .................................................................................................................................... 6
2.2 Resistentiemechanismen................................................................................................................................ 7
2.3 Opsporen van resistentiemechanismen in het labo....................................................................................... 7
3. Glycopeptide antibiotica .................................................................................................................................... 10
3.1 Werkingsmechanisme ................................................................................................................................. 10
3.2 Restentiemechanisme .................................................................................................................................. 10
4. Fosfomycine........................................................................................................................................................ 11
4.1 Werkingsmechanisme .................................................................................................................................. 11
4.2 Resistentiemechanisme................................................................................................................................ 11
Intermezzo : soorten antibiotica ............................................................................................................................ 12
5. Aminoglycosiden................................................................................................................................................. 13
5.1 Werkingsmechanisme .................................................................................................................................. 13
5.2 Resistentiemechanisme................................................................................................................................ 13
6. Macroliden en ketoliden..................................................................................................................................... 14
6.1 Werkingsmechanisme .................................................................................................................................. 14
6.2 Resistentiemechanisme................................................................................................................................ 14
7. Lincosamiden ...................................................................................................................................................... 15
7.1 Werkingsmechanisme .................................................................................................................................. 15
7.2 Resistentiemechanisme................................................................................................................................ 15
1
Moons N / Vermeulen A
, 8. Streptogamines................................................................................................................................................... 16
8.1 Werkingsmechanisme .................................................................................................................................. 16
8.2 Resistentiemechanisme................................................................................................................................ 16
9. Tetracyclines ....................................................................................................................................................... 17
9.1 Werkingsmechanisme .................................................................................................................................. 17
9.2 Resistentiemechanisme................................................................................................................................ 17
10. Glycylcyclines.................................................................................................................................................... 18
10.1 Werkingsmechanisme ................................................................................................................................ 18
10.2 Resistentiemechanisme.............................................................................................................................. 18
11. Oxazolidines...................................................................................................................................................... 19
11.1 Werkingsmechanisme ................................................................................................................................ 19
11.2 Resistentiemechanisme.............................................................................................................................. 19
12. Fluorochinolonen.............................................................................................................................................. 20
12.1 Werkingsmechanisme ................................................................................................................................ 20
12.2 Resistentiemechanisme.............................................................................................................................. 20
13. Nitro-imidazolen ............................................................................................................................................... 21
13.1 Werkingsmechanisme ................................................................................................................................ 21
13.2 Resistentiemechanisme.............................................................................................................................. 21
14. Polymyxinen ..................................................................................................................................................... 22
14.1 Werkingsmechanisme ................................................................................................................................ 22
14.2 Resistentiemechanisme.............................................................................................................................. 22
15. Sulfamiden + Trimethoprim.............................................................................................................................. 23
15.1 Werkingsmechanisme ................................................................................................................................ 23
15.2 Resistentiemechanisme.............................................................................................................................. 23
16. Nitrofuranen ..................................................................................................................................................... 24
16.1 werkingsmechanisme ................................................................................................................................. 24
16.2 Resistentiemechanisme.............................................................................................................................. 24
2
Moons N / Vermeulen A
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