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Volledige samenvatting - paard & rund - virale ziekten, prionziekten, zoönosen

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Course
Virale ziekten, prionziekten, zoönosen (G000838A)

Institution
Universiteit Gent (UGent)

Dit is een uitgebreide samenvatting van de virale ziekten, prionziekten en zoönosen van paard en rund. Gemaakt in het academie jaar 2024 en gegeven door prof Jolien Van Cleemput. Belangrijke zaken staan in het vet en zijn onderlijnd, dit maakt het studeren ook overzichtelijker. Alles wat de prof...

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Uploaded on December 25, 2024
Number of pages 126
Written in 2024/2025
Type Summary

virale ziekten
virologie
paard
rund
notities
jolien van cleemput
2024
2025
1ste master
virale ziekten
prionziekten
zoönosen
volledige samenvatting
paard en rund
diergeneeskunde
samenvatting
ugent

Institution
Universiteit Gent (UGent)
Education
Diergeneeskunde
Course
Virale ziekten, prionziekten, zoönosen (G000838A)

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VIRALE ZIEKTEN, PRIONZIEKTEN EN
ZOÖNOSEN
INHOUDSOPGAVE

INLEIDING .................................................................................................................................... 5

HERHALING ALGEMENE VIROLOGIE – BASISPRINCIPES ....................................................................................5

EQUINE INFLUENZA VIRUS / EIV ...................................................................................................17

STRUCTUUR: INFLUENZAVIRUS ............................................................................................................... 17
PATHOGENESE .................................................................................................................................. 18
SYMPTOMEN ..................................................................................................................................... 20
DIAGNOSE........................................................................................................................................ 22
BEHANDELING ................................................................................................................................... 22
PREVENTIE........................................................................................................................................ 23

EQUINE HERPESVIRUS TYPE 1 EN 4 / EHV-1, EHV-4 .......................................................................24

PATHOGENESE .................................................................................................................................. 25
SYMPTOMEN ..................................................................................................................................... 25
HERPESVIRUS REPLICATIE: LYTISCHE REPLICATIE ........................................................................................ 29
OVERZICHT PATHOGENESE ................................................................................................................... 30
CNS = EQUINE HERPES MYLOENCEPHALOPATIE (EHM) ................................................................................. 31
DIAGNOSE........................................................................................................................................ 32
BEHANDELING EN BESTRIJDING .............................................................................................................. 32
PREVENTIE........................................................................................................................................ 33

EQUINE HERPESVIRUS TYPE 2 EN 5 / EHV-2, EHV-5 .......................................................................37

SYMPTOMEN ..................................................................................................................................... 37
PATHOGENESE EHV-5 ........................................................................................................................ 37
DIAGNOSE........................................................................................................................................ 38
BEHANDELING ................................................................................................................................... 39

EQUINE HERPESVIRUS TYPE 3 / EHV-3 ..........................................................................................40

PATHOGENESE: PRIMAIRE REPLICATIE - LATENTIE – REACTIVATIE ...................................................................... 40
SYMPTOMEN ..................................................................................................................................... 40
DIAGNOSE ........................................................................................................................................ 41
BEHANDELING ................................................................................................................................... 41

PAPILLOMAVIRUS EN SARCOÏD ....................................................................................................42

SYMPTOMEN ..................................................................................................................................... 42
DIAGNOSE........................................................................................................................................ 42
BEHANDELING ................................................................................................................................... 42
BOVINE PAPILLOMAVIRUS TYPE 1 EN TYPE 2 ............................................................................................... 42
PATHOGENESE .................................................................................................................................. 43

1

, KLINISCHE TYPEN SARCOÏDEN................................................................................................................ 44
DIFFERENTIAAL DIAGNOSE .................................................................................................................... 45
DIAGNOSE........................................................................................................................................ 45
BEHANDELING ................................................................................................................................... 45

EQUINE ROTA EN CORONAVIRUSSEN ...........................................................................................48

PATHOGENESE .................................................................................................................................. 48
SYMPTOMEN ..................................................................................................................................... 49
DIAGNOSE........................................................................................................................................ 49
IMMUNITEIT ....................................................................................................................................... 50
BEHANDELING ................................................................................................................................... 51
PREVENTIE........................................................................................................................................ 51

EQUINE ARTERITIS VIRUS / EAV ....................................................................................................52

PATHOGENESE .................................................................................................................................. 52
PATHOGENESE EN SYMPTOMEN .............................................................................................................. 54
SYMPTOMEN ..................................................................................................................................... 55
IMMUNITEIT ....................................................................................................................................... 56
DIAGNOSE........................................................................................................................................ 56
CONTROLE EN PREVENTIE ..................................................................................................................... 57

EQUINE INFECTIEUZE ANEMIE VIRUS / EIAV ..................................................................................58

TRANSMISSIE..................................................................................................................................... 58
PATHOGENESE .................................................................................................................................. 59
SYMPTOMEN ..................................................................................................................................... 60
DIAGNOSE........................................................................................................................................ 60
CONTROLE EN PREVENTIE ..................................................................................................................... 61

WESTNIJLVIRUS ..........................................................................................................................62

TRANSMISSIE..................................................................................................................................... 62
SYMPTOMEN ..................................................................................................................................... 63
DIAGNOSE........................................................................................................................................ 64
BEHANDELING ................................................................................................................................... 64
CONTROLE ....................................................................................................................................... 64

BOVINE RESPIRATORY DISEASE / BRD / BOVIENE RESPIRATOIRE ZIEKTE .......................................65

ETIOLOGIE ........................................................................................................................................ 67
VIRUSSEN MET ENKEL TROPISME AHS ...................................................................................................... 67
VIRUSSEN MET O.A. TROPISME AHS ....................................................................................................... 68
TRANSMISSIE..................................................................................................................................... 69
PATHOGENESE - NAÏEF DIER .................................................................................................................. 70
PATHOGENESE – IMMUUN DIER .............................................................................................................. 71
PATHOGENESE – SECUNDAIRE BACTERIËLE INFECTIE .................................................................................... 72
PATHOGENESE – HYPERACUUT VERLOOP .................................................................................................. 72
SYMPTOMEN ..................................................................................................................................... 72
DIAGNOSE........................................................................................................................................ 73
BEHANDELING ................................................................................................................................... 74
PREVENTIE........................................................................................................................................ 74

VIRALE SVS: BOVIENE ROTAVIRUS EN BOVIENE CORONAVIRUS ....................................................78

2

, VIRALE SPIJSVERTERINGSSTOORNISSEN .................................................................................................... 78
PATHOGENESE .................................................................................................................................. 78
SYMPTOMEN ..................................................................................................................................... 79
DIAGNOSE........................................................................................................................................ 79
IMMUNITEIT ....................................................................................................................................... 79
BEHANDELING ................................................................................................................................... 81
PREVENTIE........................................................................................................................................ 81

MOND EN KLAUWZEERVIRUS .......................................................................................................83

TRANSMISSIE..................................................................................................................................... 84
PATHOGENESE: PRIMAIRE REPLICATIE – VIREMIE – SECUNDAIRE REPLICATIE ........................................................ 84
SYMPTOMEN ..................................................................................................................................... 85
DIFFERENTIAAL DIAGNOSE .................................................................................................................... 86
DIAGNOSE........................................................................................................................................ 88
BESTRIJDING ..................................................................................................................................... 90

BLAUWTONGVIRUS .....................................................................................................................92

TRANSMISSIE..................................................................................................................................... 92
PATHOGENESE .................................................................................................................................. 92
SYMPTOMEN ..................................................................................................................................... 93
DIAGNOSE, BEHANDELING EN PREVENTIE .................................................................................................. 94
UITBRAKEN ....................................................................................................................................... 95

BOVIENE PAPILLOMAVIRUSES .....................................................................................................96

TRANSMISSIE..................................................................................................................................... 96
PATHOGENESE BPV1-2 (EN 3 IN AUSTRALIË) ............................................................................................ 96
SYMPTOMEN ..................................................................................................................................... 97
PATHOGENESE BPV4 (SCHOTLAND) ....................................................................................................... 97
SYMPTOMEN ..................................................................................................................................... 97
PATHOGENESE BPV5-6....................................................................................................................... 97
SYMPTOMEN ..................................................................................................................................... 98
PATHOGENESE BPVS .......................................................................................................................... 98
PATHOGENESE BPV3,4 EN 6 ................................................................................................................ 98
PATHOGENESE BPV1,2 EN 5 ................................................................................................................ 98
IMMUNITEIT ....................................................................................................................................... 98
BEHANDELING EN PREVENTIE................................................................................................................. 99

AUJESZKY VIRUS ....................................................................................................................... 100

TRANSMISSIE TUSSEN VARKENS ............................................................................................................ 100
TRANSMISSIE VARKENS – ANDERE ZOOGDIEREN ........................................................................................ 100
PATHOGENESE RUND ........................................................................................................................ 101
SYMPTOMEN RUND ........................................................................................................................... 101
DIAGNOSE...................................................................................................................................... 102
BESTRIJDING ................................................................................................................................... 102

BOVIENE SPONGIFORME ENCEPHALOPATHIE (BSE) .................................................................... 103

PATHOGENESE ................................................................................................................................ 105
PATHOGENESE – NORMALE NEURONALE CEL............................................................................................ 105
PATHOGENESE ................................................................................................................................ 106
SYMPTOMEN ................................................................................................................................... 106

3

, DIAGNOSE...................................................................................................................................... 107
BESTRIJDING ................................................................................................................................... 107
SPECIFIEK RISICOMATERIAAL ............................................................................................................... 108
BESTRIJDING ................................................................................................................................... 108
BSE GEVAAR VOOR DE MENS? ............................................................................................................. 108
VCJD ............................................................................................................................................ 109

BOVINE VIRALE DIARREE VIRUS (BVDV) ...................................................................................... 110

CP EN NCP BIOTYPE......................................................................................................................... 110
PATHOGENESE – NCP EN CP NAÏEF DIER ............................................................................................... 111
PATHOGENESE NAÏEF DRACHTIG RUND – NCP ......................................................................................... 112
SYMPTOMEN ................................................................................................................................... 113
PATHOGENESE NAÏEF DRACHTIG RUND - CP ............................................................................................ 113
PATHOGENESE PERSISTENT VIREMISCH IMMUNOTOLERANT RUND – NCP ........................................................ 113
PATHOGENESE PERSISTENT VIREMISCH IMMUNOTOLERANT RUND – CP & NCP ................................................ 113
DIAGNOSE...................................................................................................................................... 115
BESTRIJDING VOOR 2015: SANERING VAN EEN BVD-POSITIEF BEDRIJF ........................................................... 116
BESTRIJDING NA 2015 ....................................................................................................................... 117

BOVIENE HERPESVIRUS TYPE 1 (BHV-1) ...................................................................................... 118

PATHOGENESE PRIMAIRE INFECTIE ........................................................................................................ 118
PATHOGENESE REACTIVATIE ................................................................................................................ 119
SYMPTOMEN ................................................................................................................................... 120
SYMPTOMEN MENINGO-ENCEPHALITIS (BHV-5) ...................................................................................... 121
SYMPTOMEN IPV (BHV1.2) ............................................................................................................... 121
SYMPTOMEN IPB (BHV1.2) ............................................................................................................... 121
DIAGNOSE...................................................................................................................................... 122
BEHANDELING ................................................................................................................................. 122
PREVENTIE EN ERADICATIE .................................................................................................................. 122
PREVENTIE EN ERADICATIE IN BELGIË ..................................................................................................... 124

BOOSAARDIGE CATARRAALKOORTS (BKK).................................................................................. 125

PATHOGENESE ................................................................................................................................ 125
SYMPTOMEN ................................................................................................................................... 125
DIAGNOSE – BEHANDELING - PREVENTIE ................................................................................................. 126

4

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