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samenvatting ALLE reacties organische chemie II (deel 1) $5.27
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samenvatting ALLE reacties organische chemie II (deel 1)

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een overzicht van alle reacties en mechanismen uit alle hoofdstukken van organische chemie II (2e jaar Farmaceutische wetenschappen (2024/2025))

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  • December 28, 2024
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  • 2024/2025
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ALKANEN
Hofmann eliminatie reactieE2) Ho




een
CHz


Chehe
1
D CHzCH =
CHe + INCHy + HeO
eitz
HET
H12
Halogenering
CHn + 22 Flient CHze + He




CHzChz + Bre Fr CHzCHaBr + HBr


Cytochroom -



gemedieerde hydroxylering

He Fetto- D Fe + Ho -
e
-
I

oxidatie alcohol

Grighard reagens H11
CHCHaBr hyCHMB
vorming explosieve peroxides H12


R-O-CR-O-CH-RH peroxide
CH R CH R R 0 2H
-
R
R + R 0 R O +
-



DR CH >
-



E
- -




R-0-
-

0
- -
- -
-




init
-
- .




16-0H
ALKENEN EnHen
additie HBr H6


E e += sown--- A
+ 1 Fasta -




-
additie van He/02 H6

He = e
-
HH2r he - 11 I
1 Po A #


epoxidatie H6

He = e
-H RCOOH Hie + H spiegelbeeld
étz HzCHz peroxyzuur HeHe 201

1

, Hydroborering oxidatie +
HG
H
H OH
c BradH B HH202/0H
-
-
I
=
e
D /112 - 21
- - -
-




THE in
-

# I
2
=. E




bromering HG
t

·

Brr ↑ Br Br
"i e Bri
=
I CHze
D /112-2111 +
D- anti-additie
m Br
-



244



hydrobromering
CHzCH =
CHetty
KMO HOT
roud,
,


verdund
HaOp eneh
oxidatieve doorbraak 1, 2-diolen

RI R RI


RE-CHR
HI
H
↑ &

RE-CHR"
=
D 0 + o
o'O
-
I + Hy0
10
doorbraak
permangaat
rMO HONeo
CHz
I
-CHz
CHzCHzC =
CH2Hy +=

Ozonolyse

e= e 03 .
-78
% = 0 + 0 =
e
-


&
En , HeDofHe02-
-




Elektrofiele additie

geisoleerde dienen


CherChrCh
cha (2)pH = +
D CHz-CHCHzCHzCH =
eHe
↳ Hri
of 22 I ↓
Imarkounikov) + o

HechCH
dienen
geconjugeerde

Ch
~-Ch -Ch
ee
CH-
Ch-ch Che + = + =
Che = =



e

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