CPHON Study Guide Questions and Answers
What does Hydroxyurea stimulate?
fetal hgb
What is Rituximab?
Monoclonal antibody
acts against CD20
used for Burkitts Lymphoma
Where is erythropoietin produced?
kidneys
epryhropoietin: regulates and controls the production of maturation...
CPHON Study Guide Questions and
Answers
What does Hydroxyurea stimulate? - answer fetal hgb
What is Rituximab? - answer Monoclonal antibody
acts against CD20
used for Burkitts Lymphoma
Where is erythropoietin produced? - answer kidneys
epryhropoietin: regulates and controls the production of maturation of RBCs
What is Septra and Dapsone for? - answer to prevent pneumocystis jiroveci.
What can Septra (Bactrim) cause? - answer bone marrow suppression
Imatinib is best treatment for.... - answer CML
What can Tacrolimus cause? - answer reversible posterior encephalopathy
Dactinomycin can cause? - answer radiation recall
Bleomycin can cause? - answer pulmonary fibrosis. Make sure to tell anesthesia
before being put to sleep. You cannot hyper oxygenate bc it will make it worse.
What chemos have a max dose? - answer Bleomycin
Doxorubicin 550mg/m2
What can Asparaginase cause? - answer Pancreatitis and High blood sugar
What can VP16 cause? - answer secondary AML
Alkylating agents are responsible for... - answer fertility issues. Think of transplant
chemos and high dose chemos like cisplatin, ifosphamide
What is the first line of treatment for hemolytic anemia? - answer Steroids
What drug is given for iron overload? - answer Deferoxamine it is a chelating agent
Most common childhood cancer? - answer ALL
Most common solid tumor cancer? - answer Brain tumors
,Astrocytoma: most common brain tumor
Medulloblastoma: most common malignant brain tumor
What antibiotic do you use for a line infection? - answer PCN
Pt is 10 days post transplant with pulmonary edema...what was the cause? - answer
Capillary leak syndrome from chemo
What is myeloablation therapy? - answer completely wiping out the system
preps against GVHD
ATG
prepares the bone marrow for transplant by destroying the patients circulating T
lymphocytes
What are B and T lymphocytes deficit in? - answer antibodies
Best treatment if necrotic tissue around a tumor? - answer surgery
Clinical Trials - answer 1. Max tolerated dose
2. tx on specific disease. Must have measurable diagnosis
3. new tx vs standard tx
Why limit platelet transfusions? - answer to prevent alloimmunization
also think single platelet donor
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