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Samenvatting Overzicht alle namen van antibiotica - Bacteriologie (Algemene Microbiologie)
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Overzicht van al de namen van antibiotica kan je helpen om in al die chaos toch wat overzicht te hebben :)
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1. AB die nucleotide synthese verstoreno Co-trimoxazol (foliumzuursynthese)
2. AB die inwerken op nucleïnezuren
o (Fluoro)chinolonen (DNA topoisomerase II en IV)
§ 1e generatie: nalidixinezuur
§ 2e generatie: ciprofloxacine
§ 3e generatie levofloxacine en moxifloxacine
o Metronidazole (nitro-imidazolen, toxische stof)
o Rifampicine (TXN inhiberen door binding DNA-afh RNA-polymerase)
3. AB die eiwitsynthese verstoren
o Rifampicine (afh v bron tot in welke groep hij behoort)
o Aminoglycosiden (bevriezen ribosoom)
o Tetracyclinen (interfereert met aanhechting tRNA aan mRNA)
§ 2e generatie: minocycline en doxycycline
§ 3e generatie tigecycline
o Macroliden (translocatiebeweging bij chrom over mRNA)
§ Erythromycine en clarithromycine (C14)
§ Azitromycine (C15)
o Clindamycine (lincosamiden, methylatie 23S rRNA)
o Fusidinezuur
4. AB die celwandsynthese verstoren
o Glycopeptiden (complexvorming met peptidoglycaan-precursoren)
o b-lactam (inhibitie PBP’s)
§ Penicillines
• Penicilline G, benzylpenicilline (penicillinase-gevoelig)
• Flucloxacilline (penicillinase-resistent)
• Amoxicilline (aminopenicillines)
• Piperacilline (acylureïdopenicillines)
• Temocilline (carboxypenicilline)
§ Cefalosporines
• 1e generatie: cefazoline, cefadroxil, cefalexine
• 2e generatie: cefuroxim
• 3e generatie: cefatriaxon, cefotaxim, ceftazidim
• 4e generatie: cefepim
§ Monobactams
• Aztreonam
§ Carbapenems
• Imipenem
• Peropenem
5. Middelen voor urineweginfecties
o Nitrofurantoïne
o Fosfomycine
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