NURS 6015 Exam 1 Questions With Complete Solutions
_ involves drug actions on target cells and the resulting
alterations in cellular biochemical reactions and functions
Correct Answers pharmacodynamics
__ __ is bone marrow suppression caused by drug effects it
occurs when drugs can cause cell death Correct Answers blood
dyscrasia
__ actions of the drug are effects that the drug causes in the
body that are not related to the therapeutic effect Correct
Answers secondary
__ affects the amount of a drug that reaches reactive tissues.
very little of an __ dose of a drug actually reaches reactive sites
Correct Answers pharmacokinetics
__ are most associated with GI irritation and bleeding Correct
Answers NSAIDS
__ are packets of digestive enzymes located in the cell
cytoplasm these enzymes are responsible for destroying injured
or nonfunctioning parts of the cell and for promoting cellular
disintegration when the cell dies Correct Answers lysosomes
__ are the basis of two types of cells lymphocytes and
myelocytes Correct Answers leukocytes
__ can cause serious liver toxicity Correct Answers
acetaminophen
__ causes vasodilation and heat release lowering fever and
working to relieve pain Correct Answers acetaminophen
__ drugs act on cells to cause cell death or alteration all
properties of the drug that can affect cells should be considered
when administering a __ agent Correct Answers
chemotherapeutic, chemotherapeutic
__ drugs are chemical that have been discovered to have some
therapeutic effect but that are not financially advantageous for
development into drugs Correct Answers orphan
__ drugs are drugs that have been discovered but that are not
financially viable because they have a limited market or a
narrow margin of safety. these drugs may have then been
adopted for development by a drug company in exchange for tax
incentives Correct Answers orphan
__ drugs cannot be absorbed in the acidic stomach pass through
the pyloric sphincter into the first part of the small intestine and
are absorbed there Correct Answers alkaline
__ drugs commonly cause stomatitis because they are toxic to
rapidly turning over cells such as those in the mucous
membranes of the mouth Correct Answers antineoplastic
,__ during inflammation causes rubor(redness) and calor (heat)
Correct Answers vasodilation
__ involves the destruction of engulfed proteins or bacteria
Correct Answers endocytosis
__ is a gastric acid suppressor that inhibits several CYP enzymes
and can greatly decrease drug metabolism Correct Answers
cimetidine
__ is a substance released when a cell membrane is injured
Correct Answers histamine
__ is contraindicated in children with varicella or flulike illness
because it is associated with the occurence of eye syndrome a
potentially fatal disease characterized by swelling in increased
intracranial pressure and seizures Correct Answers aspirin
__ is the passage of water and water soluble components from
the plasma into the renal tubule Correct Answers glomerular
filtration
__ or __ eruptions are common adverse drug effects Correct
Answers stomatitis or mucous membrane
__ or __ in the cell membrane allow for easier movement of
specific substances needed by the cell for normal functioning
Correct Answers channels, pores
, __ reactions can occur when a persons body makes antibodies to
a drug or drug protein. if a person is exposed to that drug at
another time a ___ response may occur. Correct Answers
allergic, immune
__ reactions to a drug are individual reactions that may be
caused by increased sensitivity to the drugs therapeutic or
adverse effects Correct Answers hypersensitivity
___ __ are very important in the functioning of neurons, muscle
cells, endocrine glands, another cell types and they play a very
important role in clinical pharmacology Correct Answers
receptor sites
___ a drug used to treat anxiety is associated with an itchy, red
rash and in some patients has caused a serious and potentially
fatal skin reactions, stevens-johnson syndrome Correct Answers
meprobamate (generic)
___ actions of the drug can be extensions of the desired effect
Correct Answers primary
___ agents work to destroy cells at various phases of their cycle.
these drugs are prescribed to kill cancer cells that are growing in
the body Correct Answers antineoplastic
___ antibiotics are toxic to rapidly dividing cells Correct
Answers antineoplastic
___ are sites of protein production within the cell cytoplasm the
specific proteins produced by a cell are determined by the
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