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Samenvatting Zezi: samenvattende tabellen neurotransmitters $3.72
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Samenvatting Zezi: samenvattende tabellen neurotransmitters

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Samenvattende tabellen over de verschillende receptoren voor de verschillende neurotransmitters. Met daarbij de effecten van deze op de receptor en belangrijke te onthouden info. Tweede tabel met verschillende belangrijke zones in verband met de geziene neurotransmitters.

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  • January 5, 2025
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Neurotransmitter Receptor Type Locatie/Functies Aanvullende informatie

Acetylcholine (ACh) Nicotinerge receptoren Ionotroop - Snelle synaptische Ligand-gated ionkanaal;
(nAChR) transmissie laat Na⁺ en K⁺ door

- neuromusculair Nm - Corticale activering en
- neuronaal Nn motoriek

Muscarinerge Metabotroop - Aandacht, geheugen, G-eiwit-gekoppelde
receptoren (mAChR) parasympathische regulatie receptor
5 subtypes (M1-M5) 2nd m: cAMP & IP3

Noradrenaline (NA) α1-adrenerge Metabotroop - Vasoconstrictie Activeren fosfolipase C via
receptoren Gq-eiwitten
- controle gladde spiercellen
postsynaptisch Daling K-concentratie

α2-adrenerge Metabotroop - vasoconstrictie Gi-eiwit-gekoppeld; remt
receptoren cAMP-productie Stijging K-
concentratie, daling Ca-
presynaptisch
concentratie

β1-adrenerge Metabotroop - Hartslagverhoging Gs-eiwit-gekoppeld;
receptoren verhoogt cAMP-productie

Daling K-concentratie

β2-adrenerge Metabotroop - Bronchodilatatie Gs-eiwit-gekoppeld
receptoren
- vasodilatatie

Dopamine (DA) D1-receptoren (D1&D5) Metabotroop - Excitatoire effecten Gs-eiwit-gekoppeld;
verhoogt cAMP-productie
- Regulatie beloning en
motoriek D1 in striatum

D2-receptoren Metabotroop - Inhibitoire effecten Gi-eiwit-gekoppeld;
(D2,D3&D4) verlaagt cAMP-productie
- Autoregulatie en
verslavingsgedrag D2 in striatum, D3 in
nucleus accumens

Serotonine (5-HT) 5-HT1-receptoren Metabotroop - Regulatie stemming, angst, Gi-eiwit-gekoppeld;
(Dia 3 voor subtypes) thermoregulatie verlaagt cAMP-productie

5-HT2-receptoren Metabotroop - Perceptie, hallucinaties Gq-eiwit-gekoppeld;
verhoogt intracellulaire
calcium

5-HT3-receptoren Ionotroop - Braakreflex- Misselijkheid Ligand-gated ionkanaal;
laat Na⁺ en K⁺ door

5-HT6/7-receptoren Metabotroop - limbisch systeem: gemoed Gi-eiwit-gekoppeld;
en stemming verhoogt cAMP-productie

Histamine (H) H1-receptoren Metabotroop - Regulatie waakzaamheid Gq-eiwit-gekoppeld;
en allergische reacties betrokken bij slaap-
waakcyclus en
- arousal
immuunreacties
- feeding/
Link met werkgeheugen
energiemetabolisme

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