Summary

Samenvatting pathologie spijsverteringsstelsel

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Course
Spijsvertering (E0C09A)

Institution
Katholieke Universiteit Leuven (KU Leuven)

Book
Aandoeningen van het spijsverteringsstelsel

Samenvatting vak Spijsvertering, gegeven in 1e master GNK. Volledige samenvatting van powerpoint, collegenotities en boek, samen met de foto's. Deel gegeven door Prof. Dr. Roskams en Prof Dr De Hertogh.

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Summarized whole book? No
Which chapters are summarized? Hoofdstuk 3 en 8
Uploaded on January 7, 2025
Number of pages 46
Written in 2024/2025
Type Summary

histologie
pathologie
1e master gnk
spijsvertering
samenvatting
kul

Book Title:Aandoeningen van het spijsverteringsstelsel

Author(s):Frederik Nevens

Edition:Unknown
ISBN:9789463797108
Edition:1

Institution
Katholieke Universiteit Leuven (KU Leuven)
Education
Geneeskunde
Course
Spijsvertering (E0C09A)

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2024-
2025

Pathologie
spijsverteringsstelsel
PROF DR DE HERTOGH EN PROF DR ROSKAMS
JOZEFIEN CEULEMANS

,Bovenste GI-tractus ................................................................................................................... 4
De slokdarm............................................................................................................................ 4
1. Slokdarm: ontsteking ................................................................................................. 4
De normale slokdarm ..................................................................................................... 4
Reflux ziekte ................................................................................................................... 4
Andere vormen van oesofagitis ..................................................................................... 5
2. Slokdarm: Barret ........................................................................................................ 6
De maag: ontsteking............................................................................................................... 7
Gastritis .............................................................................................................................. 7
Acute hemorrhagische gastritis...................................................................................... 7
Chronische gastritis ........................................................................................................ 7
andere vormen gastritis ................................................................................................. 9
Peptische maagulcus .......................................................................................................... 9
Maag: tumor ......................................................................................................................... 10
algemeen .......................................................................................................................... 10
Inflammatoire darmziekten .................................................................................................... 10
Coeliakie ............................................................................................................................... 10
Inleiding ............................................................................................................................ 10
Definitie ............................................................................................................................ 11
Microscopie .................................................................................................................. 11
Differentieeldiagnose ................................................................................................... 11
Etiologie en pathogenese ............................................................................................. 11
Rol van PO ........................................................................................................................ 13
Diagnose ....................................................................................................................... 13
Opvolgen van patiënten onder glutenvrij dieet ........................................................... 13
Verwikkelingen detecteren .......................................................................................... 13
Colitis algemeen + specifieke vormen.................................................................................. 13
Microscopie normale colon .............................................................................................. 13
Symptomen en classificatie .............................................................................................. 14
Diagnose ........................................................................................................................... 14
Rol van PO ........................................................................................................................ 14
Acute zelflimiterende colitis ......................................................................................... 14
Specifieke infecties ....................................................................................................... 15
CIBD: colitis ulcerosa en ziekte van Crohn ........................................................................... 16
Definities .......................................................................................................................... 16

, Rol van PO ........................................................................................................................ 16
Chronische colitis ............................................................................................................. 16
Colitis ulcerosa ............................................................................................................. 17
Ziekte van Crohn........................................................................................................... 18
Differentieel diagnose .................................................................................................. 19
Microscopische colitis .......................................................................................................... 19
Colon neoformaties ................................................................................................................. 20
Colonpoliepen ...................................................................................................................... 20
Niet-neoplastische poliepen ............................................................................................ 20
Peutz-Jeghers poliep .................................................................................................... 21
Juveniele poliep ............................................................................................................ 21
Inflammatoire pseudopoliep ........................................................................................ 22
Nl mucosa ..................................................................................................................... 22
Hyperplastische poliep ................................................................................................. 23
Tussenvormen .................................................................................................................. 23
Sessiel serrated letsel ................................................................................................... 23
...................................................................................................................................... 24
Traditioneel serrated adenoom ................................................................................... 24
Neoplastische poliepen .................................................................................................... 24
Tubulair adenoom ........................................................................................................ 25
Villeus adenoom ........................................................................................................... 25
Andere .......................................................................................................................... 26
Coloncarcinoom ................................................................................................................... 26
Omvang van het probleem ............................................................................................... 26
Associaties, moleculaire pathologie ................................................................................. 26
Ontwikkeling................................................................................................................. 26
Presentatie colonCA ......................................................................................................... 27
Symptomen .................................................................................................................. 27
Rol van patholoog ............................................................................................................ 28
Type tumor ................................................................................................................... 28
Tumor graad ................................................................................................................. 29
Functionele lever pathologie .................................................................................................. 29
Algemene histologie en pathologie ..................................................................................... 29
Hele context leverhistologie ............................................................................................ 30
Hepatitis ............................................................................................................................... 31

, Spectrum van tekens ........................................................................................................ 31
Milde lobulaire hepatitis .............................................................................................. 31
Interfasehepatitis ......................................................................................................... 31
Bridging necrose ........................................................................................................... 32
Specifieke kenmerken hepatitis ....................................................................................... 32
Hepatitis C .................................................................................................................... 32
Hepatitis B .................................................................................................................... 33
Auto immune hepatitis................................................................................................. 33
...................................................................................................................................... 33
Toxische/xenobiotica ................................................................................................... 33
Steatohepatitis of metabool syndroom ............................................................................... 33
Fe depositie ...................................................................................................................... 35
Alfa-1 trypsine deficiëntie ................................................................................................ 36
Cholestatische leverziekten.................................................................................................. 36
Kenmerken van cholestase algemeen.............................................................................. 36
Specifieke ziekten ............................................................................................................. 37
Cholangiopathie: DD/ ................................................................................................... 38
Cirrogenese .......................................................................................................................... 39
Patronen ........................................................................................................................... 39
Regeneratie hepatocyten ................................................................................................. 40
Definitie cirrose ................................................................................................................ 40
Leverpathologie tumoren ........................................................................................................ 40
Goedaardige hepatocellulaire tumoren ............................................................................... 40
Focale nodulaire hyperplasie ........................................................................................... 41
Hepatocellulair adenoom ................................................................................................. 41
HNF1alfa mutatie ......................................................................................................... 41
B-catenine mutatie ....................................................................................................... 42
Inflammatoire adenomen ............................................................................................ 42
Carcinomen .......................................................................................................................... 42
Hepatocarcinogenese....................................................................................................... 42
Verschil dysplasie – maligne kanker................................................................................. 43
Kenmerken hooggradige dysplasie - kanker ................................................................ 43
Classificatie ....................................................................................................................... 43
Kankerstamcel .............................................................................................................. 43
Samenvatting.................................................................................................................... 45

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