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UNE Medical Biochemistry Midterm Review Questions and Answers 100% Pass | Revised

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UNE Medical Biochemistry Midterm Review Questions and Answers 100% Pass | Revised Ribose and NADPH - A family presents for genetic counseling. The couple has two female children who are alive and well; however, their infant son recently died in the nursery with severe hemolysis (lysis of red b...

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  • January 8, 2025
  • 11
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • UNE Biochemistry
  • UNE Biochemistry
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EmilyCharlene
UNE Medical Biochemistry
Midterm Review Questions and
Answers 100% Pass | Revised

Ribose and NADPH - ✔✔A family presents for genetic counseling. The couple has two female children

who are alive and well; however, their infant son recently died in the nursery with severe hemolysis

(lysis of red blood cells) and jaundice. The wife recalls she lost a brother in infancy with severe hemolysis,

induced after a viral infection. The physician suspects a glucose-6-phosphate dehydrogenase deficiency,

this would result in a deficiency in which of the following compounds in red blood cells?


Transketolase - ✔✔A patient presents to the emergency department with lactic acidosis. A deficiency in

thiamine (TPP) is suspected and this will be consistent with a decrease in the activity of following

enzymes?


UDP-Glucose - ✔✔Galactose 1-phosphate is initially converted to glucose 1-phosphate and requires

which of the following compounds?


Thiamine diphosphate - ✔✔Which of the following cofactors is required for transketolase activity?


Glyceraldehyde 3-phosphate - ✔✔Aldolase B facilities a reaction that cleaves fructose 1-phosphate into

two 3-carbon molecules that will enter glycolysis as which of the following compounds?


Glycolysis - ✔✔High levels of activity of the non-oxidative portion of the pentose phosphate pathway

will directly produce intermediates of which of the following pathways?




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 1

, Glucose 6-phosphate dehydrogenase - ✔✔The major regulatory step of the pentose phosphate pathway is

catalyzed by which enzyme?


VLDL particles - ✔✔Insulin stimulates fatty acid synthesis in the liver. These fatty acids are transported

to the adipose tissue as which of the following?


Free fatty acids - ✔✔A young woman goes to work without eating breakfast and skips lunch. In this

scenario, which of the following pathways is providing substrates used to generate ATP in the liver?


Glucagon - ✔✔Caffeine is a natural inhibitor of phosphodiesterase. If you were to consume a large

amount of coffee you would likely see a prolonged response to which of the following stimulants or

hormones?


They enhance transcription when bound to receptors - ✔✔A teenage female presenting with lack of

menstruation (amenorrhea) is found to have a dysfunctional steroid receptor characteristic of androgen

insensitivity syndrome. Which of the following statements accurately describes steroid hormones?


Intracellular receptors - ✔✔Steroid hormones bind which of the following types of receptors?


They are specific to a chemical messenger - ✔✔Which of the following is a characteristic of all receptors?


Free fatty acids - ✔✔What is the primary oxidized fuel for skeletal muscle in the fasted state?


Cyclic-AMP response element binding protein (CREB) - ✔✔cAMP elicits multiple cellular responses. The

effects of cAMP on gene transcription are directly mediated by which of the following DNA binding

proteins?


GLUT4 - ✔✔An individual is recently diagnosed with Type 2 diabetes. In this individual, hyperglycemia

may in part be due to inactivity of which of the following glucose transporters on skeletal muscle?




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