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UNE Biochemistry Final Exam Questions and Answers 100% Pass

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  • UNE Biochemistry

UNE Biochemistry Final Exam Questions and Answers 100% Pass What are the direct products of Beta Oxidation? - NADH FADH2 Acetyl CoA What does Acetyl CoA get used for - ketogenesis allosterically activates Pyruvate Carboxylase An 11yo girl is brought into the emergency department by her fathe...

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  • January 8, 2025
  • 16
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • UNE Biochemistry
  • UNE Biochemistry
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EmilyCharlene
UNE Biochemistry Final Exam
Questions and Answers 100% Pass

What are the direct products of Beta Oxidation? - ✔✔NADH


FADH2


Acetyl CoA


What does Acetyl CoA get used for - ✔✔ketogenesis


allosterically activates Pyruvate Carboxylase


An 11yo girl is brought into the emergency department by her father. He reports that she has recently

been very thirsty and needing to make frequent trips to the bathroom. At her soccer game today, she

complained of lightheadedness and symptoms did not resolve even after drinking a power beverage. A

rapid dipstick test revealed glucose in her urine and further diagnostics indicate with a diagnosis of Type

1 Diabetes. Evaluation of the liver would indicate an increased amount of which of the following

processes? - ✔✔Ketogenesis


What is the role of adipose in metabolism? - ✔✔storage of triacyglycerols


appetite regulation, coagulation, immunity, reproduction


A 5yo female is brought into the ED by her mother. She is a type 1 diabetic and has not taken her insulin

while away at a day camp. The child is unresponsive. Which of the following enzymes is phosphorylated

and active under these conditions? - ✔✔hormone sensitive lipase




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 1

,An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this

time, which of the following is the primary oxidizable substrate in the skeletal muscle? - ✔✔free fatty

acids


An individual is on a hunger strike and has not eaten in 13 days. Which of the following best describes

their metabolic state? - ✔✔The brain will be preferentially oxidizing ketones


In the fasted state, fatty acyl-CoAs are transported across the mitochondrial membrane. The transport of

fatty acids via carnitine palmitoyl transferase I (CPTI) can be directly inhibited by which of the following

compounds? - ✔✔Malonyl CoA


Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the

following enzymes? - ✔✔Hormone Sensitive Lipase


A well, 2-year-old girl presents to the clinic with symptoms of a viral illness. Her parents report she has

had bouts of vomiting and diarrhea over the last 24 hours. This morning they could barely wake her from

her crib and she was very weak. Laboratory tests show low blood glucose (hypoglycemia) and elevated

liver enzymes. There are no ketones present in her urine. The child is hospitalized and glucose is

administered by I.V. Additional laboratory analysis showed elevated medium-chain fatty acyl carnitines

in blood and 6-8 carbon dicarboxylic acids in the urine. Which of the following abnormalities is the most

likely diagnosis for this child? - ✔✔Defect of medium-chain acyl-dehydrogenase


A 22-year-old woman engaging in a political protest goes on a hunger strike on a prominent corner in a

city park. She refuses all offers of food except for water through the first 2 weeks. Under these conditions

there is a decreased reliance on which of the following pathways for fuel? - ✔✔Gluconeogenesis


ATP can be generated by many metabolic pathways in the body. Which of the following processes

generates the most ATP? - ✔✔Fatty acid beta oxidation




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 2

, In liver, which of the following key inhibitory events ensures that newly synthesized palmitoyl-CoA is

not immediately oxidized? - ✔✔Inhibition of carnitine-palmitoyl transferase-I (CPT-I) by malonyl-CoA.


An increase in the ratio of insulin to glucagon will increase which of the following enzymes? -

✔✔hormone sensitive lipase decreases


acetyl CoA carboxylase increases


Phosphofructokinase 2 increases


glycogen synthase increases


NADPH is essential for fatty acid synthesis and can be generated by which two enzymes? (+ indicates

NADPH can be produced by the enzyme; - indicates the enzyme does not produce NAPDH) For G6P

Dehydrogenase, Malic Enzyme, and Pyruvate Dehydrogenase Complex - ✔✔+, +, -


A defect in the thioesterase subunit of fatty acid synthase would impair which of the following activities

of the enzyme complex? - ✔✔Liberation of newly assembled palmitate from the enzyme


Malate can be converted to pyruvate in the cytosol. Which of the following compounds is directly

generated in this conversion and is essential for fatty acid synthesis? - ✔✔NADPH


Which of the following enzymes is correctly paired with its allosteric inhibitor? - ✔✔Acetyl-CoA

carboxylase: palmitoyl-CoA


An increase in the ratio of insulin to glucagon leads to which of the following metabolic shifts? -

✔✔Acetyl-CoA carboxylase will become dephosphorylated and active


In the case of a deficiency of biotin, which of the following enzymes required for fatty acid metabolism

will be impaired? - ✔✔Acetyl-CoA carboxylase




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 3

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