1.A nurse working in radiology administers iodine to a patient who is having a
ff ff ff ff ff ff ff ff ff ff ff ff ff
computerized axial tomography (CAT) scan. A nurse working on an oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14-
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month-old child as a routine immunization. Which branch of pharmacology best
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describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved ff ff ff ff ff ff ff ff ff ff ff ff
with clinical pharmacology or pharmacotherapeutics, which is a branch of
ff ff ff ff ff ff ff ff ff ff
pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
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disease. The nurse working in radiology is administering a drug to help diagnose a
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disease. The nurse working on an oncology unit is administering a drug to help treat a
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disease. Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body, and pharmacokinetics is ff ff ff ff ff ff ff ff ff ff
how the body acts on the drug.
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Cognitive Level: Comprehension ff ff
Difficulty: Easy
ff ff
Integrated Process: Nursing process ff f f ff
2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4
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hours as needed for pain for a motor vehicle accident victim. The nurse is aware that
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there is a high abuse potential for this drug; therefore, morphine is categorized as a:
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A) Schedule I drug ff ff
B) Schedule II drug ff ff
C) Schedule III drug ff ff
D) Schedule IV drug ff ff
Ans: B
Response:
Narcotics such as morphine are considered schedule II drugs because of the high
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abuse potential with severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser abuse
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potential than schedule II drugs and an accepted medical use. Schedule IV drugs have
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Integrated Process: Communication and documentation ff f f ff ff
3.A nurse working for a drug company is involved in phase III drug evaluation studies.
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Which of the following might the nurse be responsible for during this stage of drug
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development?
ff
, Chapter 1: Introduction to Drugs ff ff ff ff
A) Working with animals who are given experimental drugs ff ff ff ff ff ff ff
B) Monitoring drug effects in patients who are selected to participate in a study, ff ff ff ff ff ff ff ff ff ff ff ff
who have the disease that the drug is meant to treat
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C) Collecting records of symptoms that participants experience while taking a ff ff ff ff ff ff ff ff ff
drug and determining whether they are caused by the disease or the drug
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D) Informing healthy, young volunteer participants of possible risks that could ff ff ff ff ff ff ff ff ff
occur from taking an experimental drug
ff ff ff ff ff ff
Ans: C
Response:
Phase III studies involve use of a drug in a vast clinical market where patients are
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asked to record any symptoms they experience while taking the drugs. Nurses may be
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responsible for helping collect and analyze the information to be shared with the
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Food and Drug Administration (FDA). Use of animals in drug testing is done in the
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preclinical trials. A select group of patients who are involved in phase II studies
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participate in studies where the participants have the disease the drug is intended to
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treat. These patients are monitored closely for drug effects. Phase I studies involve
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healthy human volunteers who are usually paid for their participation. Nurses may
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observe for adverse effects and toxicity.
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Cognitive Level: Comprehension ff ff
Difficulty: Moderate
ff f f
Integrated Process: Nursing Process ff f f ff
4. Which of the following concepts is considered when generic drugs are substituted for
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brand-name drugs?
ff ff
A) Bioavailability
B) Critical concentration ff
C) Distribution
D) Half-life
Ans: A
Response:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation ff ff ff ff ff ff ff ff ff ff ff ff ff ff
and is available to act on body cells. Binders used in a generic drug may not be the
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
same as those used in the brand-name drug. Therefore, the way the body breaks down
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and uses the drug may differ, which may eliminate a substitution. Critical
ff ff ff ff ff ff ff ff ff ff ff ff
concentration is the amount of a drug that is needed to cause a therapeutic effect.
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
Distribution is the phase of pharmacokinetics that involves the movement of a drug to ff ff ff ff ff ff ff ff ff ff ff ff ff
the body's tissues. A drug's half-life is the time it takes for the amount of drug to
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
decrease to one-half of the peak level.
ff ff ff ff ff ff ff
Cognitive Level: Analysis f ff
ff Difficulty: Difficult f f
Integrated Process: Teaching/learning ff f f
5. A nurse is teaching her patient about the use of over-the-counter (OTC) drugs. Which
ff ff ff ff ff ff ff ff ff ff ff ff ff
ff of the following statements best informs the patient about their safe use?
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A) ―OTC drugs are products that are available without prescription for self- ff ff ff ff ff ff ff ff ff ff
treatment of minor complaints.‖
ff ff ff ff
B) ―OTC drugs are considered medications and should be reported on a drug ff ff ff ff ff ff ff ff ff ff ff
history.‖ ff
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