Class notes
DNA structure & function (complete)
- Course
- BIO 181 (BIO181)
- Institution
- Arizona State University - Tempe
Unit 3 lectures 1&2, Bio 181, includes all information for DNA structure and function
[Show more]
Seller
Follow
Content preview
DNA Structure & FunctionCell division
under tight regulation
History of DNA discovery
Friedrich miescher: Physician
isolated phosphate rich
isolated phosphate-rich chemicals from white blood cells (leukocytes).
He named these chemicals nuclein because they were isolated from the
nuclei of the cells.
Would eventually be known as DNA
Griffith Experiment:
bacterial transformation: process in which external DNA is taken up by a
cell, thereby changing its morphology and physiology.
R strain was non-pathogenic
S strain was pathogenic
Hershey & chase
Wanted to know what genetic material got passed on
1 group was labeled by DNA and other was labeled by protein
—> Bacteria was infected by phage
took DNA out of bacteria to see if the protein or DNA got passed on
Discovery of DNA
Roslind Franklin
X-Ray crystallographer
DNA Structure & Function 1
, took photo of DNA (Doubel helix)
DNA (an intro)
Controls most of our characteristics
Key words
Gene: Segment of DNA that codes for a protein
Alleles: Different forms of gene present on each copy of the same
chromosome
Trait: characteristic of an individual
Histome: Protein that DAN is round around
Exon: Inside of gene
intron: inside of gene
Transcription: DNA making into mRNA
Translation: mRNA made into protein
Genotype: DNA composition or genetic makeup
Phenotype: physical expression for traits
Structure
Needs: Phosphate, sugar & nitrogenous base
mRNA Uses ribose sugar
DNA uses deoxyribose sugar
held together by phosphodiester bond
nucelotides bonded by hydrogen bonds
base stacking (weak non-polar interaction) with van der Waals forces
antiparallel: Both strands are running in different directions
Important for transcription, replication, allows for complimetary
DNA Structure & Function 2
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller daisycrawford007. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
64450 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 15 years now