Med Administration
>
- Classifications
• pharmaceutical class - mechanism of action, - medication orders
physiologic effect, chemical structure
• client name, drug name, indication, dosage, route,
• therapeutic class - clinical indication for drug frequency, time, provider signature
>
- pharmacodynamics - how drugs alter cell physiology and high alert medications - drugs associated with
affect body increased risk of client harm when error
- pharmacokinetics (ADME) - absorption, distribution, • insulin, opiates, narcotics, heparin, potassium
metabolism, excretion chloride IV
• most metabolized by liver, kidneys >
- Injection angles
• first pass effect - oral meds pass through liver, lower • intramuscular: 90
concentration in circulation - deltoid, ventrogluteal, vastus lateralis
• primary excretion organ is kidneys • subcutaneous: 45-90
- if unable to metabolize and excrete, toxicity - upper arm, abdomen, thigh, upper back
>
-
levels
• intradermal: 5-10
• therapeutic range - concentration in blood that
produces desired effect without toxicity
• peak level - highest plasma concentration
• trough level - lowest concentration
• half life - time it takes for 1/2 of blood concentration
to be eliminated
>
-3 checks of administration
• when med obtained by nurse from med drawer
• during preparation of med
• at clients beside
> rights of med administration
• right client
• right medication
• right dose
• right route
• right time
• right documentation
>
-
med reconciliation
• whenever care of client is transfered
• review clients current medications, address omissions
and duplication
> Serious adverse drug event (ADE)
-
• must be reported to FDA to improve safety outcomes
>
- Adverse drug reactions
• allergies - anaphylaxis
• toxic effect
• paradoxical
• drug interactions
• stevens - johnson syndrome
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