Summary
Summary Topic 6 Non Specific Defense
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Edexcel Biology Topic 6 Non Specific Defence, Immunology, Histamines, Skin,Macrophages, Phagocytosis
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Non-SpecificNon specific immune response attacks all pathogens
despite antigens
S.I units
Skin
1
Physical barrier prevents pathogens >
-
waxy
- -
.
fibrous
-
> Keratin e
structure
protein >
-
secondary
rich
↳ Impenetrable
2
. Biological /commensall
species
- Skin
flora bacterial
↳ dont cause disease (non pathogen
compete will
man for
pathogens and resources
-
space
↳ better
adapted pathogens
3 .
Lipids fatty acids with antimicrobial properties
- oil
- sebum
Mouth
- >
lysozyme enzymes are
exocytosed from
cells
↳ break down all wall peptide links
↳ in tears
Stomach HC1 lower
pH-enzymes affected
- ->
denature
bonds and ionic bonds
↳
hydrogen
commensals
gut flora
-
Blood
clotting preventing
>
-
,
pathogens entering
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