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Samenvatting - cardio nier: stoornissen in de waterhuishouding $3.20
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Samenvatting - cardio nier: stoornissen in de waterhuishouding

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Samenvatting van de elektrolyt/volumestoornissen in de waterhuishouding van de nier (Na, K, V, acidose, alkalose): de oorzaken en bijhorende klinische presentaties.

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  • January 20, 2025
  • 3
  • 2023/2024
  • Summary
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Cardiovasculair stelsel: nier
Stoornissen id waterhuishouding

Hypovolemie, Vdepletie, ondervulling
-  vocht input path hypothalamus: dorstgevoel
-  vocht output GI (braken, bloeding), ADH (diabates insipidus), perspiratio
insensibilis en sensibilis
Na-verlies > hypoaldosteronisme

1. Hyperosmotische deshydratatie R/ 0,9%NaCl IV of 5% glucose
verlies van zuiver water (diabetes insipidus, zweten) of hypotoon vocht
2. Iso-osmotische deshydratatie
Verlies van isotoon vocht (bloeding, braken, diarree)
3. Hypo-osmotische deshydratatie
Renaal Na verlies, verlies van hypertoon vocht

Veneuze drukdaling eerst
Arteriele drukdaling
-> hypovolemische shock indien >25% bloedverlies
-> perfusie huid, splanchnisch, coronair, cerebraal
-> sympatische tonus: tachycardie, zweten
Renale drukdaling
-> hematocriet en plasma-albumine
-> oligurie, osm urine, lage FENa
->  BUN/PCr

Hypervolemie, Vexpansie, overvulling
- input polydipsie (psychotisch, path hypothalamus)
NaCl 
- output abno ADH (SIADH)

Iso-osmotische, hyperosmotische en hypo-osmotische overhydratatie

Hyponatriëmie < 135mmol
- Renaal Na verlies > hypoaldosteronisme
- water input > polydipsie
- water output > abno ADH secretie (SIADH), GFR door effectief circulerend V

Chronisch: weinig symptomen door osmotische adaptatie (vrijlating osmolieten > cellen)
Acuut: hersenoedeem (H20 EC -> IC)

R/ waterrestrictie > dilutionele hyponatriëmie Niet te snel owv osmotische
Na toediening > Vdepletie - oraal demyelinisatie thv axonen vd pons
- hypertoon NaCl 3% IV (genormaliseerde osm als
hyperosmolair ervaren)

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