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The Course Pharmaceutical Technology and Biopharmacy 2 summary
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een samenvatting voor het vak ptb2 van de bachelor farmacie, pharmaceutical technology and biopharmacy
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Pharmaceutical Technology and Biopharmacy 2 (PTB2)Day 1 – Visser
Pharmacy preparations
1. Introduction
2. Basic operations
3. Oral liquid preparations
4. Dermal preparations
5. Rectal preparations
Product care
- Ensure availability of the proper medicine
- In the right dosage form
- Good quality at the time of administration
Pharmaceutical care
- Pharmaceutical care
- Product care
What is a medicine
- API that is put in a dosage form
- Dosage form consist of API and Excipients
o API and dosage form determine the biopharmaceutical properties
Excipients
- Facilitate production
- Improve quality of the product
- Optimize performance of the product
- Increase patient acceptability and compliance taste
Slide 7
- Patient needs to know how to use the product
- Product has a functionality determined by the composition API + excipients
Types of action
- Systemic drug enters circulation API reaches its site of action via the bloodstream
- Local
Slide 9
, Legal status of medicines
- Branded products
- Commercially available
- Licensed marketing authorization
Extemporaneous pharmacy preparations
- Prescription of a product that is not available industrially
- Tailor-made for the patient personalized medicine
- Unlicensed
Pharmacy preparation
- Manufacture of unlicensed pharmaceutical preparations by or at the request of pharmacies
Why pharmacy preparations
- Optimize pharmacotherapy for a patient
o
Commercial products insufficiently meets specific requirements
o
Commercial products are unavailable
o
Tailor-made approach
- To increase patient compliance
o Better acceptance by the patient
When pharmacy preparations
- Dose adjustments children
- Dosage form adjustment other route of administration nausea rectal medication
- Hypersensitivity to excipients
- Unavailability of a product on the market
- Modification of industrial preparation
- Short shelf life radio pharmaceuticals
- Investigational medicinal product
Types of pharmacy preparations
- Compounded from raw materials
o Drug substances + excipients
- Manipulated (commercially available) licensed dosage forms
o Pulverizing tablets to make capsule
o Conversion of oral solid dosage form into oral liquid dosage form
- Preparation prior to use
o Reconstitution of injection fluid
o Filling medication pump
Standardized formulations
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