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PHARMACODYNAMICS-EXAM 2 QUESTIONS WITH 100% VERIFIED ANSWERS!!
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PHARMACODYNAMICS-EXAM 2 QUESTIONS WITH 100% VERIFIED ANSWERS!!
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PHARMACODYNAMICS-EXAM 2QUESTIONS WITH 100% VERIFIED
ANSWERS!!
1 of 44
Term
While most drug receptors are proteins, they can also be...
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nucleic enzymes or lipids proteins
gtp, gdp, adenylyl cyclase nuclear receptors
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2 of 44
Term
-dose of drug administered
-dose concentration
-drug concentration at site of action
-drug in tissues
-drug metabolized or excreted
THESE ALL REFER TO...
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Affinity = 1/EC50 or IC50 pharmacokinetics
therapeutic window mass action
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, 3 of 44
Term
Term used to describe the amount of attraction between a
drug and a receptor. It is related to the amount of drug
that is required to bind to the unoccupied receptor.
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Affinity = 1/EC50 or IC50 Affinity = ec50 + Ic50
Affinity = receptor Affinity = drug concentration /
occupancy / drug efficacy receptor density
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4 of 44
Term
What are 3 specific components of pharmacodynamics?
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1. Drug binding causes
1. receptor
binding receptor DIMERIZATION
2.signal 2.When the enzyme domain
transduction is catalytically active, it leads
3. physiological to cross phosphorylation
effect
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