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Final Exam: NR 507/ NR507 (New 2025/ 2026 Update) Advanced Pathophysiology Review| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Chamberlain $11.99
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Final Exam: NR 507/ NR507 (New 2025/ 2026 Update) Advanced Pathophysiology Review| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Chamberlain

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Final Exam: NR 507/ NR507 (New 2025/ 2026 Update) Advanced Pathophysiology Review| Questions & Answers| Grade A| 100% Correct (Verified Solutions)- Chamberlain

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  • January 27, 2025
  • 28
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • nr507 nr 50
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Finall Exam:l NRl 507/l NR507l (Newl 2025/l
2026l Update)l Advancedl Pathophysiologyl
Review|l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solutions)-l
Chamberlain

QUESTION
hypothalamic-pituitaryl axis


Answer:
interconnectionl ofl thel hypothalamusl andl pituitaryl tol regulatel thel levelsl ofl certainl
endocrinel hormonesl throughl al complexl seriesl ofl negativel feedbackl systems

-l hypothalamusl responsiblel forl releasingl hormonesl meaningl pituitary,l anteriorl andl
posteriorl canl notl releasel itsl hormonesl withoutl messagel orl stiml hormonesl froml thel
hypothalamus
ex:l thyroidl releasingl hormonel isl sentl byl hypothalamusl whichl thenl stimulatesl pituitaryl
tol releasel thyroidl hormonel whichl thenl targetsl thel thyroidl wherel hormonel actsl onl
thyroid




QUESTION
Thyroidl Disorders


Answer:
hyperthyroidism,l hypothyroidism




QUESTION
Hypothyroidism
-l whatl arel thel namel ofl thel types?
-l howl arel typesl different?

,-l inl whol isl itl mostl common?
-l whatl %l ofl population?


Answer:
Primaryl Hypothyroidism:l thyroidl stimulatedl properlyl butl isl unablel tol producel enoughl
thyroidl hormonesl forl thel bodyl tol functionl properly.l Thyroidl glandl itselfl hasl problem.l
Ex:l arel Hashimoto'sl diseasel andl autoimmunel thyroidl disease.

Secondaryl hypothyroidism:l thel pituitaryl glandl isl notl stimulatingl thel thyroidl enough.l
probleml NOTl withl thyroid

-l underactivel thyroid
-l thel mostl commonl disorderl ofl thyroidl function
-l affectsl betweenl .1%l andl 2%l ofl thel USl population
-l morel commonl inl womenl andl elderly




QUESTION
t4l andl t3
-l wherel arel theyl releasedl from?
-l whatl %l ofl eachl isl secreted?l Whichl isl more/less?


Answer:
t4l isl exclusivelyl froml thel thyroidl gland

80%l ofl hormonel secretedl byl t4
20%l ofl hormonel secretedl byl t3




QUESTION
Autoimmunel Thyroidl Disease
-l whatl causesl it?
-l whatl levelsl willl bel elevated?
-l whatl levelsl depressed?
-l whatl levelsl normal?
-l whatl doesl itl leadl to?

, Answer:
-l thyroidl isl infiltratedl withl sensitizedl t-lymphocytes

-l thyroidl autoantibodiesl presentl inl blood.l Elevatedl anti-thyroidl antibodyl titers

-l patientsl willl havel euthyroid.l Thyroidl hormonel levelsl willl lookl normal.l b/cl ofl this,l
needl tol testl forl anti-thyroidl antibodyl titers

-l thisl canl alll leadl tol hypothyroidism




QUESTION
Pathologyl ofl Subclinicall Hypothyroidism
-l whatl isl it?
-l whatl isl compensation?
-l whatl happensl tol thyroidl hormonel andl TSH?
-l whatl aboutl thyrotropin?


Answer:
involvesl thel disruptionl ofl thel feedbackl loopl b/wl hypothalamusl andl pituitaryl glandl andl
thyroidl gland

-l thyroidl glandl unablel tol producel adequatel thyroidl hormonesl leadingl tol increasedl
secretionl ofl TSHl byl pituitaryl gland.l Thel additionall TSHl isl compensatingl forl lowerl
thyroidl hormonel butl thyroidl stilll unablel tol producel enough

-l thyrotropinl levell ofl 10mlUl perl literl isl usedl tol distinguishl b/wl mildl orl morel severe




QUESTION
Hyperthyroidism
-whatl isl it?
-l whatl isl thel mostl commonl cause?l Explainl thel pathol pfl thisl commonl cause?
-l whatl arel otherl causes?


Answer:
-l excessivel activityl ofl thel thyroidl gland

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