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Test Bank for Modern Blood Banking & Transfusion Practices 7th Edition by Denise M. Harmening| 9780803668881| All Chapters 1-29| LATEST $17.99
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Test Bank for Modern Blood Banking & Transfusion Practices 7th Edition by Denise M. Harmening| 9780803668881| All Chapters 1-29| LATEST

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Test Bank for Modern Blood Banking & Transfusion Practices 7th Edition by Denise M. Harmening| 9780803668881| All Chapters 1-29| LATEST

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  • MODERN BLOOD BANKING & TRANSFUSION PRACTICES
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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice
d


Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis d d


b. Luebering-Rapoport shunt d. Methemoglobin reductase d d d




2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed. The
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unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most accurate?
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a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm d d d c. 1 to 2 µm d d d


b. 2 to 4 µm d d d d. 4 to 6 µmd d d d d




4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues
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when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% d




5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count d d


b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a result
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of loss of RBC membrane?
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a. Spherocytes c. Burr cells d


b. Target cells d. Schistocytes
d d




7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend
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c. An individual donating blood for a relative
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d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism d c. Oxygen transport d


b. Porphyrin synthesis d d. Signal transduction
d d




9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
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d 10. What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate d d d d d


b. 40% protein, 8% lipid, 52% carbohydrate d d d d d


c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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d 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level. d d d


b. Loss of red blood cell function. d. Decreased glucose consumption.
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d 12. Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD d d




d 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. d




d 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
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the bone marrow?
d d d


a. 30% c. 10%
b. 50% d. 25% d d




d 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d. Regulation of pH d d d d




d 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
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of alkalosis?
d d


a. Normal c. Shift to the right d d d


b. Shift to the left d. None of the above
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d 17. Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A d d




d 18. The ABO blood groups were discovered in 1901 by whom?
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a. Charles Drew c. Loutit and Mollisond d d


b. Karl Landsteiner d. Edward Lindeman
d d d




d 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in the
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corner of the department until discovered 36 hours later. What would the appropriate action be for the blood
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banker?d


a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be
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OK to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has been
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compromised. d


c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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accept the unit into inventory. d d d d


d. If the platelets appeared OK and passed the platelet swirl test after being placed on the
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agitator, they could be accepted into the inventory.
d d d d d d d d




d 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
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a. Glycolysis c. Pentose phosphate shunt d d


b. Luebering-Rapoport shunt d. Methemoglobin reductase d d d




d 21. All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation curve
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except:
a. Increased 2,3-DPG. d

b. 50% O2 saturation to tissues.d d d d


c. Decreased 2,3-DPG. d


d. Decreased hemoglobin affinity for O2. d d d d




d 22. What is the normal platelet count range per cubic millimeter?
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a. 100 to 350 d c. 50,000 to 200,000
d d d


b. 150,000 to 350,000 d. 350,000 to 500,000
d d d d d




d 23. What cryoprotective agent is added to red blood cells upon freezing?
d d d d d d d d d d d


a. Dextrose c. Glycerol
b. Adsol d. All of the above d d d d




d 24. If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
d d d d d d d d d d d d d d d d d d


a. 1°C to 6°C d d c. 35°C to 37°C d d


b. 20°C to 24°C d d. 1°C to 10°C
d d d d




d 25. What role do platelets play in hemostasis?
d d d d d d d


a. Maintenance of vascular integrity d d d


b. Initial arrest of bleeding by platelet plug formation
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c. Stabilization of the hemostatic plug d d d d


d. All of the above d d d




d 26. Which of the following best describes "integral" membrane proteins?
d d d d d d d d d


a. Reside at the cytoplasmic surface of membrane d d d d d d


b. Span the entire membrane surface d d d d


c. Form the red blood cell cytoskeleton d d d d d


d. None of the above d d d




d 27. How is stroma-free hemoglobin solution prepared?
d d d d d d


a. Outdated red blood cells are concentrated, and stroma is removed.
d d d d d d d d d


b. Outdated red blood cells are diluted with saline, and stroma is removed.
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c. Outdated red blood cells are lysed, and stroma is removed. d d d d d d d d d


d. None of the above d d d




d 28. What is the normal life span of an RBC?
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a. 100 days d c. 120 hours d


b. 120 days d d. 2 days d d




d 29. Regarding loss of RBC membrane deformability, all of the following are true except:
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a. Increase in ATP level. d d d


b. Decrease in ATP level. d d d




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