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PATH 375 - Hematolymphoid pathology Study Guide Exam And Actual Answers. $10.49
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PATH 375 - Hematolymphoid pathology Study Guide Exam And Actual Answers.
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Myeloid tissue - Answer (a) located in bone marrow •blood cell precursors (b) located in the blood • blood cells [erythrocytes, platelets, granulocytes, monocytes] Lymphoid tissue - Answer - located in lymphoid organs: • thymus, lymph nodes, spleen, MALT - loacted in blood: ...

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  • February 5, 2025
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PATH 375 - Hematolymphoid pathology
Study Guide Exam And Actual Answers.
Myeloid tissue - Answer (a) located in bone marrow

•blood cell precursors

(b) located in the blood

• blood cells [erythrocytes, platelets, granulocytes, monocytes]



Lymphoid tissue - Answer - located in lymphoid organs:

• thymus, lymph nodes, spleen, MALT

- loacted in blood:

•lymphocytes



Pluripotent stem cells in bone marrow give rise to... - Answer myeloid and lymphoid precursors
(constant source of cells)



Hematopoiesis - Answer - myeloid cells produced from multipotential cells in bone marrow

- 4 cell lines



4 cell lines - Answer each line undergoes differentiation into committed cells:

1) erythroid/megakaryocytic

2) macrophage/granulocytic

3) eosinophilic

4) mast cell/basophilic



Lymphopoiesis - Answer -Occurs in lymphoid tissue

-is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally
known as lymphoid hematopoiesis.

,Three types of blood cells - Answer -Red blood cells

-white blood cells

-platelets



RBC - Answer Main function is to carry O2



WBC - Answer main function is to fight infections



Platelets - Answer main function is clotting



Three types of white blood cells - Answer 1. Granulocytes: neutrophils, eosinophils, basophils

2. Monocytes

3. Lymphocytes



Volume of blood in body - Answer 5 litres (cells + plasma)



Hematocrit - Answer Ratio of cells to total volume of blood



Plasma - Answer Fluid component of blood before clotting (need to anti-coagulate)



Serum - Answer Fluid component of blood after clotting



Complete blood count (CBC) and Differential is a commonly ordered lab test - Answer CBC: count of
each type of blood cell (platelet, RBC, WBC)

Differential: different types of WBC present



Blood smear - Answer Assess morphology (shape) of blood cells



Hemoglobin: molecular structure - Answer - 4 globin chains (2 alpha, 2 beta)

, - 1 globin chain has heme molecule, Fe, O2



RBC shapes - Answer



Hemoglobin (Hb) - Answer • Molecule that carries oxygen, present in red blood cells

- consists of 4 globin (polypeptide) chains (2 alpha, 2 beta)

- a globin chain has a heme molecule, heme molecule contains Fe

- oxygen is carried by the heme molecule (4 per Hb)



To make hemoglobin, need... - Answer Fe, B12, B6, folate



Average lifespan of RBC - Answer 120 days



Breakdown of RBC occurs in - Answer Spleen

-removes old and/or defective red blood cells



Hemoglobin recycling - Answer - bilirubin is breakdown product of heme

- bilirubin is sent to liver, secreted into bile, enters small intestine where it could be reabsorbed and re-
utilized or lost in feces



bilirubin - Answer is a YELLOW compound that occurs in the normal catabolic pathway that breaks
down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste
products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of
the heme molecule which thereafter passes through various processes of porphyrin catabolism,
depending on the part of the body in which the breakdown occurs



Hematolymphoid pathology

Overview - Answer RBC disorders

WBC disorders

Bleeding disorders

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