100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Samenvatting hoorcollege 7 $3.21
Add to cart

Summary

Samenvatting hoorcollege 7

 16 views  0 purchase
  • Course
  • Institution

Samenvatting hoorcollege 7 - Virusziekten uu

Preview 2 out of 6  pages

  • June 18, 2020
  • 6
  • 2019/2020
  • Summary
avatar-seller
Virusziekten samenvatting HC.7
Membrane function is a key process in cellular life. You have three kinds of membrane
fusion:
1. Intracellular fusion
 Cell secretory pathway
 ER to Golgi and back
 Golgi to plasma membrane and back
 Synaptic transmission
 Organelle fusion
 Mitochondrial fusion
 Endosome-lysosome fusion
 Mostly mediated by SNAREs.
2. Cell-Cell fusion
3. Fusion of virus membrane with host cell membrane
 Enveloped viruses needs to fuse their membrane with that of the host to deliver the
viral content
 Mediated by viral fusion proteins




There are different routes of virus entry. But there are two common things in every entry:
attachment and crossing the host membrane. In all cases, and all steps of the viral entry are
mediated by specialized proteins!!

 Attachment  is mediated by virion protein(s) binding to specific host surface
molecule(s) such as membrane proteins, lipids or the carbohydrate moieties present either
on glycoproteins or glycolipis.




 Crossing the host membrane

,  Pore-mediated entry




 Lysis or membrane permeabilization (many non-enveloped viruses)




 Membrane fusion (enveloped viruses)




Biolayer piophysics
 The intrinsic tendency of a lipid bilayer is to adapt and keep a flat shape (some lipids
spontaneously form monolayers of different curvatures)
 In the lipid bilayer the two monolayers will tend, energetically, to have the same lipid
composition
 The bilayer will be completely symmetric with respect to its mid plane
 Bilayer will oppose curving by external forces

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller annickkooij. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $3.21. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

52510 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$3.21
  • (0)
Add to cart
Added