Summary
FA-BA302 Cardiovasculaire aandoeningen Samenvatting
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Samenvatting van alle behandelde onderwerpen inc. de benodigde herhaling uit FA-BA106. Gemaakt in studiejaar .
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FA-BA302Cardiovasculaire
aandoeningen
Samenvatting
Michelle
,Inhoud
Week 1; Hart, bloedvaten en de nier ............................................................................................. 6
Leerdoelen........................................................................................................................................... 6
Anatomie en fysiologie van hart en bloedvaten (werking & regulatie circulaire systeem) ................ 6
Anatomie van het hart .................................................................................................................... 6
Fysiologie bloedsomloop ................................................................................................................. 7
Anatomie bloedvaten ...................................................................................................................... 9
Bloedvoorziening van het hart ...................................................................................................... 11
Hartfalen ........................................................................................................................................ 11
Anatomie en fysiologie van de nier ................................................................................................... 12
Anatomie nier ................................................................................................................................ 12
Fysiologie van de nier .................................................................................................................... 13
Regulatie van de bloeddruk............................................................................................................... 14
Begrippen en afkortingen .............................................................................................................. 14
RAAS .............................................................................................................................................. 16
Barroreflex ..................................................................................................................................... 17
Regulatie osmose .......................................................................................................................... 18
Medicatie........................................................................................................................................... 19
Bètablokkers .................................................................................................................................. 19
Calciumantagonisten ..................................................................................................................... 19
ACE-remmers................................................................................................................................. 20
Angiotensine-I-antagonisten (ARB) ............................................................................................... 20
Renine inhibitors ........................................................................................................................... 21
Diuretica ........................................................................................................................................ 21
Nitraten ......................................................................................................................................... 22
Week 2; Primaire hemostase ...................................................................................................... 25
Leerdoelen......................................................................................................................................... 25
Bloedplaatjes/ trombocyten ............................................................................................................. 25
α-granula ....................................................................................................................................... 25
Dense bodies ................................................................................................................................. 26
Activering van de primaire hemostase.............................................................................................. 26
Regulatie primaire hemostase .......................................................................................................... 27
Geneesmiddelen die aangrijpen op de primaire hemostase ............................................................ 28
Plaatjesaggregatieremming als behandeling ................................................................................ 29
Fysisch-chemische eigenschappen besproken in het werkcollege ................................................... 30
Michelle 2
,Week 3; Secundaire hemostase .................................................................................................. 31
Leerdoelen......................................................................................................................................... 31
De stollingscascade ........................................................................................................................... 31
Activering van de secundaire hemostase .......................................................................................... 31
Extrinsieke activatie....................................................................................................................... 32
Intrinsieke activatie ....................................................................................................................... 32
Voor beide activatie routes ........................................................................................................... 32
Hemofilie ....................................................................................................................................... 33
Regulatie van de secundaire hemostase ........................................................................................... 33
Antitrombine ................................................................................................................................. 33
Proteïne-C-systeem ....................................................................................................................... 33
Regulatie van weefselfactorfunctie ............................................................................................... 34
Fibrinolyse ..................................................................................................................................... 35
Overzicht stollingscascade + regulatie .............................................................................................. 36
Geneesmiddelen die aangrijpen op de secundaire hemostase ........................................................ 36
Extra leerpunten uit het werkcollege ................................................................................................ 38
Combinatie primaire- & secundaire hemostase ............................................................................... 39
Week 4; Bloedvetten .................................................................................................................. 40
Leerdoelen......................................................................................................................................... 40
Cholesterolmetabolisme ................................................................................................................... 40
Atherosclerose .................................................................................................................................. 41
Hoe ontstaat atherosclerose ......................................................................................................... 41
Stabiel / instabiel vaatlijden .......................................................................................................... 43
Klinische parameters van bloedvetten .............................................................................................. 43
Geneesmiddelen die effect uitoefenen op de bloedvetten .............................................................. 44
Week 5; arteriële hypertensie ..................................................................................................... 47
Cardiovasculair risicomanagement ................................................................................................... 47
Risicofactoren HVZ ........................................................................................................................ 47
Risicocategorieën .......................................................................................................................... 47
De SCORE-risciotabel ..................................................................................................................... 48
Lichamelijke klachten bij hypertensie ............................................................................................... 48
Arteriële hypertensie streefwaardes ................................................................................................ 48
Beleid ................................................................................................................................................. 49
Casus.................................................................................................................................................. 50
Samenvattingsplaatje; bloeddruk regulators .................................................................................... 51
Michelle 3
, Week 6; CVA, atherosclerose en DVT .......................................................................................... 52
Leerdoelen......................................................................................................................................... 52
Bloedstolling op het verkeerde moment .......................................................................................... 52
Beleid na het doormaken van een TIA of een herseninfarct ............................................................ 52
Beleid diep veneuze trombose .......................................................................................................... 53
Atherosclerose .................................................................................................................................. 53
Casussen ............................................................................................................................................ 54
Patiënt 1: Arteriële trombose........................................................................................................ 54
Patiënt 2: Veneuze trombose ........................................................................................................ 56
Week 7; coronaire doorbloedingsstoornissen .............................................................................. 58
Leerdoelen......................................................................................................................................... 58
Angina Pectoris .................................................................................................................................. 58
Klachten angina pectoris ............................................................................................................... 58
Risicofactoren ................................................................................................................................ 59
Balans tussen zuurstofvraag & -aanbod ........................................................................................ 59
Pijn bij Angina Pectoris .................................................................................................................. 60
ECG bij Angina Pectoris ................................................................................................................. 60
Beleid Angina Pectoris ....................................................................................................................... 61
Casus.................................................................................................................................................. 62
Week 8; acuut coronair syndroom .............................................................................................. 63
Myocardinfarct .................................................................................................................................. 63
Classificatie van AMI...................................................................................................................... 64
Klachten AMI ................................................................................................................................. 64
Overzicht ....................................................................................................................................... 66
Reperfusietechnieken........................................................................................................................ 66
Dotteren ........................................................................................................................................ 66
Fibrinolyse ..................................................................................................................................... 67
CABG → coronaire bypass............................................................................................................. 68
Keuze voor reperfusietechniek...................................................................................................... 68
Casus.................................................................................................................................................. 68
Week 9; doorgemaakt CVA en myocardinfarct ............................................................................ 70
Atriumfibrilleren ................................................................................................................................ 70
Symptomen ................................................................................................................................... 70
ECG ................................................................................................................................................ 70
Antitrombotische beleid bij atriumfibrilleren ................................................................................... 70
Michelle 4
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