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Exam (elaborations)

AAB Molecular Diagnostics

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AAB Molecular Diagnostics

Institution
AAB
Course
AAB











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Institution
AAB
Course
AAB

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Uploaded on
March 19, 2025
Number of pages
184
Written in
2024/2025
Type
Exam (elaborations)
Contains
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1 of 294

Term



small interfering RNA (siRNA)



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functional intermediates of
structural components of ribosomes
RNA interference

, lipids that store energy enzymes that break Down proteins


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2 of 294

Term



One of the most common genetic disorders (incidence 1 in 200-400)



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Obesity Hemochromatosis




Sickle Cell Anemia Polycythemia


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, 3 of 294

Definition



-single-stranded DNA template
-DNA primer
-DNA polymerase
-normal deoxynucleosidetriphosphates (dNTPs)
-modified nucelotides (dideoxyNTPs) that terminate DNA strand
elongation



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Requirements to identify
Hemochromatosis- primarily caused
Gonorrhoeae & Chlamydia
by mutation in what gene?
(Urogential tract pathogens)




Requirements of Sanger
Characteristics of Closed Systems Sequencing (Chain-Termination
method)


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4 of 294

Term



Example of X-linked dominant inheritance

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turner syndrome, klinefelter
albinism, achondroplasia
syndrome




duchenne/becker muscular
tay-sachs disease, phenylketonuria
dystrophy, fragile-x syndrome


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5 of 294

Term



What is done with a depurinated gel?



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gel is soaked in HCl solution to
gel is treated with alcohol to
remove purine bases from
precipitate proteins
purine backbone




gel is frozen to preserve the dna gel is heated to evaporate excess
structure moisture


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