NR565- ADVANCE PHARMACOLOGY WITH
COMPLETE QUESTIONS AND ANSWERS
Which schedule drugs can APRNs prescribe? - CORRECT ANSWER-II-V
Who determines and regulates prescriptive authority? - CORRECT ANSWER-State Board of
Nursing
How does limited prescriptive authority impact patients within the healthcare system? -
CORRECT ANSWER-Longer wait times to sign a prescription
Limit practitioners that are needed in rural areas
Unequal relationships between providers.
Independent practitioners= more patients being seen= lessens the patient/provider load
What are the key responsibilities of prescribing? - CORRECT ANSWER-Safe and competent
practice
Understanding of the drugs, reactions, and pharmacology
Be aware of the age group you are prescribing to
What should be used to make prescribing decisions? - CORRECT ANSWER-Documented
provider-patient relationship
Not prescribing for family or friends
Documenting a thorough H&P, including discussions with the patient, and drug
monitoring/titrating.
Cost, guidelines, availability, interactions, side effects, allergies, hepatic and renal function,
need for monitoring, and special populations
,Be familiar with pharmacokinetic and pharmacodynamic changes of older adults and how
that would translate to baseline information needed to prescribe. - CORRECT ANSWER-
increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Beer's Criteria- What is it and Why is it important - CORRECT ANSWER-Recommendations of
medications inappropriate for elderly (65 and older)
Prevents adverse drug reactions
Impacts/outcomes of polypharmacy - CORRECT ANSWER--increase risk for medication
interactions
CYP450 inhibitors
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?) -
CORRECT ANSWER-inhibit metabolism, increase blood levels of medications
Examples
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit
juice, quinidine
"VISA credit card debt INHIBITS spending on designers like CK to look GQ"
Examples of CYP450 inducers
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?) -
CORRECT ANSWER-Speed up metabolism of drugs (drug is cleared faster), drug has lesser
effect (decrease blood levels of drug)
, Examples
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
"Bullshit Crap GPS INDUCES rage"
What happens when someone has a poor metabolism phenotype? - CORRECT ANSWER-
medications metabolized slower, medication might not work or put them at risk for side-
effects
What does the U.S. Food and Drug Administration regulate when it comes to medications? -
CORRECT ANSWER-Whether the drug is safe, effective, and benefits of a drug outweigh the
risks
Reasons for medication non-adherence - CORRECT ANSWER-patients never filling/refilling
prescriptions (resulting in therapeutic failure)
multiple chronic disorders
multiple prescription medications
multiple doses per day for each medication
drug packaging that is difficult to open
multiple prescribers
changes in the regimen (adding meds, changes in dose or timing)
cognitive or physical impairment (reduction in memory, hearing, visual, color, or manual
dexterity)
living alone
recent discharge from the hospital
low literacy
inability to pay for meds
personal conviction that a drug is unnecessary or the dosage is too high
presence of side effects
COMPLETE QUESTIONS AND ANSWERS
Which schedule drugs can APRNs prescribe? - CORRECT ANSWER-II-V
Who determines and regulates prescriptive authority? - CORRECT ANSWER-State Board of
Nursing
How does limited prescriptive authority impact patients within the healthcare system? -
CORRECT ANSWER-Longer wait times to sign a prescription
Limit practitioners that are needed in rural areas
Unequal relationships between providers.
Independent practitioners= more patients being seen= lessens the patient/provider load
What are the key responsibilities of prescribing? - CORRECT ANSWER-Safe and competent
practice
Understanding of the drugs, reactions, and pharmacology
Be aware of the age group you are prescribing to
What should be used to make prescribing decisions? - CORRECT ANSWER-Documented
provider-patient relationship
Not prescribing for family or friends
Documenting a thorough H&P, including discussions with the patient, and drug
monitoring/titrating.
Cost, guidelines, availability, interactions, side effects, allergies, hepatic and renal function,
need for monitoring, and special populations
,Be familiar with pharmacokinetic and pharmacodynamic changes of older adults and how
that would translate to baseline information needed to prescribe. - CORRECT ANSWER-
increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Beer's Criteria- What is it and Why is it important - CORRECT ANSWER-Recommendations of
medications inappropriate for elderly (65 and older)
Prevents adverse drug reactions
Impacts/outcomes of polypharmacy - CORRECT ANSWER--increase risk for medication
interactions
CYP450 inhibitors
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?) -
CORRECT ANSWER-inhibit metabolism, increase blood levels of medications
Examples
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit
juice, quinidine
"VISA credit card debt INHIBITS spending on designers like CK to look GQ"
Examples of CYP450 inducers
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?) -
CORRECT ANSWER-Speed up metabolism of drugs (drug is cleared faster), drug has lesser
effect (decrease blood levels of drug)
, Examples
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
"Bullshit Crap GPS INDUCES rage"
What happens when someone has a poor metabolism phenotype? - CORRECT ANSWER-
medications metabolized slower, medication might not work or put them at risk for side-
effects
What does the U.S. Food and Drug Administration regulate when it comes to medications? -
CORRECT ANSWER-Whether the drug is safe, effective, and benefits of a drug outweigh the
risks
Reasons for medication non-adherence - CORRECT ANSWER-patients never filling/refilling
prescriptions (resulting in therapeutic failure)
multiple chronic disorders
multiple prescription medications
multiple doses per day for each medication
drug packaging that is difficult to open
multiple prescribers
changes in the regimen (adding meds, changes in dose or timing)
cognitive or physical impairment (reduction in memory, hearing, visual, color, or manual
dexterity)
living alone
recent discharge from the hospital
low literacy
inability to pay for meds
personal conviction that a drug is unnecessary or the dosage is too high
presence of side effects
