Exam Questions and CORRECT Answers
Pharmacodynamics - CORRECT ANSWER - How a drug affects the body
Receptors - CORRECT ANSWER - Large molecules that interact with and mediate the action
of drugs
Up-regulation - CORRECT ANSWER - Increases the number of receptors; if an antagonist
causes this can get rebound effects if the drug is abruptly withdrawn
Down-regulation - CORRECT ANSWER - Decreases the number of receptors; if an agonist
causes this can limit the length of time the patient can take the drug
Agonists - CORRECT ANSWER - Activators; stimulates receptors.
Promotes normal function of the protein (receptor).
Antagonists - CORRECT ANSWER - Blockers; occupy receptors without stimulating them,
prevent other molecules from occupying that site.
Silences the protein and prevents function.
Beers Criteria - CORRECT ANSWER - List of potentially inappropriate medications that are
best avoided by older adults in most circumstances or with specific disease or conditions
Partial agonists - CORRECT ANSWER - Bind to receptors but stimulate only some of them,
can help prevent too extreme of a response
Therapeutic index - CORRECT ANSWER - Ratio of dose that causes ADRs to therapeutic
dose, safer to have a wide range than a narrow range