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NSG 6005 MIDTERM EXAM STUDY GUIDE / NSG6005 MIDTERM EXAM STUDY GUIDE (LATEST, 2020): SOUTH UNIVERSITY | UPGRADED AND PERFECT GUIDE, DOWNLOAD TO SCORE A| $15.49   Add to cart
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NSG 6005 MIDTERM EXAM STUDY GUIDE / NSG6005 MIDTERM EXAM STUDY GUIDE (LATEST, 2020): SOUTH UNIVERSITY | UPGRADED AND PERFECT GUIDE, DOWNLOAD TO SCORE A|

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  • NSG6005 (NSG6005)
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  • SOUTH UNIVERSITY

NSG 6005 MIDTERM EXAM STUDY GUIDE / NSG6005 MIDTERM EXAM STUDY GUIDE (LATEST, 2020): SOUTH UNIVERSITY | UPGRADED AND PERFECT GUIDE, DOWNLOAD TO SCORE A|

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  • August 26, 2020
  • 125
  • 2020/2021
  • Study guide

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  • download to score a|
  • nsg 6005 midterm exam study guide nsg6005 midterm exam study guide latest
  • 2020 south university | upgraded and perfect guide

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  • SOUTH UNIVERSITY
  • NSG6005 (NSG6005)
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NSG 6005 Advanced Pharmacology Midterm—Study Guide

There will be 75 questions on the Midterm. Most will be multiple choice. There are a
couple True/False and 5 matching questions. I suggest you review your PowerPoints and
Textbook Assignments. I hope this study guide is helpful

Make sure you know the following topics very well.

• When a medication is listed below, make sure you know all about it and how
to apply it to different patient situations: What disease process it is used
for?, how does it work?, when should it not be used?, adverse effects,
pros/cons, interactions, patient education factors (should it be taken w/ food?
At bedtime?), tapering, preliminary and post treatment labs, black box
warnings/CI, etc.

• If a disease process is mentioned below—know how to diagnose and
recommended treatment guidelines.



1) General principles of pharmacokinetics and dynamics?


PHARMACOKINETICS- What the body does to the drug”
Absorption –Entry of drug to the blood stream. Usually depends on passive diffusion of drug
through cell membranes.
• Absorption depends on: blood flow at site, drugs lipid soluability (>lipic,
>soluabililty that directly penetrate the memebrane), local PH and drug ionization
(non-ionized absorb better), pharmaceutical processing (coatings and additives.
• Blood brain barrier: allow lipid soluable only. May pump out any drug that it sees
as foreign, hard to treat CNS infections.
• Placenta: allows lipid drugs so does not protect from lipid soluable drugs, which
is why pregnant women are limited to drugs. Know gestation age.
•

, 2

Distribution
: fat ratio changes may alter distribution, especially a people age.

• Fat soluable drugs may be accumulated: weight loss will release these drugs.

• Water soluable drugs are affected by dehydration

Biotransformation (Metabolism) : Drugs become more hydrophilic (water soluable) for
excretion.

• Also referred to as the P450 system or cytochrome P450 system. (a group
of enzymes in the liver identified for their ability to breakdown drugs.)

• Hepatic“First Pass Effect” (parenteral (IV or IM) meds bypass this
enzymatic effect)




• breaks PO meds down to some degree, some are protected with coating
but they don’t always work




• Metabolites
Usually less active, less toxic, easier

• to excrete

• Prodrugs - inactive in form given but metabolized to active drug (ex:
enalapril)

• Liver function determined by liver enzymes

• Failing liver produces fewer enzymes, drugs available longer: caution

•

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