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  3. Vrije Universiteit Amsterdam (VU)
  4.  
  5. Microbiology and Toxicology

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Summary Toxicology Lecture 1

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  • Course
  • Microbiology and Toxicology
  • Institution
  • Vrije Universiteit Amsterdam (VU)
  • Book
  • Brock Biology of Microorganisms, Global Edition

Orderly and clear summary of lecture 1 what is discussed during the toxicology lectures. With this summary you will save a lot of time. I passed this course with a 7,5. Good luck :)

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  • Yes
  • December 7, 2020
  • 4
  • 2019/2020
  • Summary

Subjects

  • biomedical sciences
  • biomedical sciences
  • toxicology
  • microbiology

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  • Vrije Universiteit Amsterdam (VU)
  • Bachelor Biomedical Sciences
  • Microbiology and Toxicology
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1  review

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By: MKrispin1 • 3 year ago

Translated by Google

Clearly, and contains almost all the dust! Friday afternoon exam, WISH ME LUCK <3

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By: biomedicalsciencesvu • 3 year ago

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Thank you!! Hopefully gone well:)

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By: MKrispin1 • 3 year ago

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Thank you, and made at once!! Tomorrow immunology exam and bought your summary again, but I'm not going to make it this time I think :( good summary, and WISH ME LUCK <3) #cringe

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By: biomedicalsciencesvu • 3 year ago

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How nice to hear! Success:)

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Content preview

Toxicology – Lecture 1 – Chapter 1 – Introduction to Toxicology

1.1 Definition and scope
Toxicology; branch of science that deals with poisons
(gif)
Poison; any substance that causes a harmful effect to
living organism

Toxicology also includes the study of harmful effects
caused by physical phenomena; radiation and noise
etc.

All things are poisonous and nothing is not
poisonous. Only the dose makes something not being
a poison.

Toxicology is a multidisciplinary science;
Biolgoy/Chemistry/Biochemistry/Physiology/genetics/mathematics/statistics/medicine
/pharmacology

There are different subdisciplines in the toxicology
o Descriptive toxicology; animal studies
o Mechanistic toxicology; mode of action (molecule – gene – cell)
o Analytical toxicology; contaminant (verontreinigd) levels in the body
o Food toxicology; compounds in food
o Occupational toxicology; chemicals at work
o Developmental toxicology; effect on the developing embryo
o Reproduction toxicology; effects on the reproduction
o Clinical toxicology; treatment of poisoning
o Forensic toxicology; proof of intended poisoning
o Environmental toxicology; environmental pollution; individuals
o Ecotoxicology; environmental pollution; ecosystems
o Regulatory toxicology; setting thresholds

Toxicity is a cascade of events;
1. Exposure
2. Distribution and metabolism
3. Interaction with cellular macromolecules / expression of a toxic end point

Phases in toxic response;
Phases in toxic response
1. Exposure (blootstelling)

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