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Sumario Esquemas de farmacologia
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Esquemas de farmacologia
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FÁRMACO CINÉTICA MECANISMO DE ACCIÓN ACCION INDICACIONES RAM CONTRAINDICACIONFARMACOLOGICA
PARACETAMOL - VO, VR, IV. Inhibe las PG a nivel Analgésico. -Dolor leve/moderado, no -Daño hepático.
- 3-4h de vida media. periférico (COX1 y COX2). Antitérmico. visceral ni inflamatorio. -Daño renal.
- Sinergismo con codeína. -Fiebre. -Poco alergizante.
- 25% unión a prot. -No antiagregante ni Intoxicación: administrar N-
plasmáticas: pocas gastrolesivo. acetil cisteína.
interacciones.
AAS -VO. Inhibe las PG a nivel Analgésico. -Dolor leve/moderado no -Gastrolesivo.
-3-4h de vida media. periférico (COX1 y COX2). Antitérmico. visceral. -Peligro de hemorragia. ULCERAS
- 80-90% unión a Irreversible. (7dias) Antiinflamatorio. -Dolor inflamatorio. -Broncoco DIABETICOS
Prot.plasmáticas: muchas Antiagregante es bajo -Fiebre. Constricción: asma, EMBARAZAS
interacciones. (reversible) -Antiagregante plaquetario urticaria, broncoespasmo.
(50-150mg/día) -Daño renal.
-Contraindicado en
ulcerados, anticoagulados.
METAMIZOL -VO, IM, IV. Inhibe las PG a nivel central. Analgésico. -Dolor intenso. -Gastrolesivo por VO.
-6h de vida media. Antitérmico. -Dolor visceral. -Alteraciones hemáticas.
-Absorción rápida y Antiinflamatorio. -Dolor inflamatorio. - Por vía IV debe ir diluido y
efecto inmediato. -Fiebre. con el goteo lento, sino
-No se une a PrPl: pocas -Relaja ms liso. puede provocar shock por
interacciones. -No antiagregante. HTA
RESTO DE Inhiben las PG a nivel Analgésicos. (dolor -Dolor leve-moderado. -Gastrolesivos. < que AAS
AINES. periférico (COX1 y COX2). leve-moderado) -Dolor inflamatorio. -Daño renal.
Naproxeno Antitérmicos. -Fiebre. -Daño hepático.
Antiinflamatorios. -Alteraciones hemáticas:
Ibuprofeno
Antiagregantes elevación transaminasas,
Diclofenaco
(reversible) agranulocitosis.
Dexketoprofeno
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