Resumen acerca de los antiinflamatorios no esteroideos, clasificación clínica, efectos adversos, en que patologías se pueden emplear, ejemplo de medicamentos,
ANTIINFLAMATORIOS NO ESTEROIDEOS (AIINES)
● AAINES bloquean la vía de la ciclo- oxigenasa.
● Los CORTICOIDES son antiinflamatorios ESTEROIDEOS, bloquean la fosfolipasa 2, impiden la actividad de la
vía de la lipooxigenasa y de la ciclooxigenasa.
● EJEMPLO: Hidrocortisona, betametasona, beclometasona y prednisona.
Salicilatos
● Ácido acetilsalicílico: Depende la dosis el efecto que tiene
● Diflunisal
● Fosfosal
● Salicilamida
● Suldasalazina
● Ácido gentísico
Para-amino-fenoles
● Acetaminofeno/paracetamol: Mejor antipirético
● Fenazopiridina
● Propacetamol
● Derivados Pirazólicos
● Fenilbutazona→ Oxifenilbutazona
● Metamizol: Antipirético, antiespasmódico y antiinflamatorio
● Propifenazona
Derivados del Ácido Propiónico: Funcionan más como antiinflamatorios y
analgésicos
● Ácido Tiaprofénico
● Dexketoprofeno
● Fenoprofeno
● Flurbiprofeno
● Ibuprofeno
● Ketoprofeno
● Naproxeno
Indolacético:
● Acematacina
● Proglumatecina
● Indometacina: Favorece conducto arterioso, disminuir contracciones
● uterinas en embarazadas
● Sulindac
● Pirrolacético:
● Ketorolaco: Mayor actividad analgésica. Cualquier tipo de dolor
● Tolmetina
Oxicams: Padecimientos articulares (dolor). Actúan mucho sobre COX 2, no
selectivos
● Lornoxicam
● Piroxicam
● Meloxicam
● Tenoxicam
● Derivados del Ácido Antranílico
● Ácido Flufenámico
● Ácido Meclofenámico
● Ácido Mefenámico
● Floctafenina
Inhibidores de la COX-2
● Celecoxib
● Parecoxib
● Rofecoxib
● Valdecoxib
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