Geleidende deel:
• Zuiveren, opwarmen en bevochtigen van ingeademde lucht (+ reuk + geluid)
• Continue luchtstroom verzekeren dmv kanalen met rigide basisopbouw die over
nodige flexibiliteit beschikken
• Neusholte, nasofarynx, larynx, trachea, bronchi, bronchiolen, terminale bronchiolen
Respiratoire deel:
• Structuren waar eigenlijke gasuitwisseling plaatsvindt
• Dunne wand om uitwisseling mogelijk te maken
• Respiratoire bronchiolen, ducti alveolares, alveolen
2
, NEUSHOLTE
• Functie:
– Opwarmen van ingeademde lucht door dens capillair netwerk onder het
epitheliale oppervlak
– Bevochtiging van ingeademde lucht door kleine seromuceuze kliertjes
– Zuiveren van ingeademde lucht door mucuslaag geproduceerd door
seromuceuze kliertjes en slijmbekercellen
– Immunologisch door oppikken van allergenen en antigenen in de ingeademde
lucht (dendritische cellen in epitheel en lymfoide elementen in lamina
propria) en IgA productie (plasmacellen in lamina propria)
• 2 componenten in linker en rechterneusholte:
– Vestibulum nasi
– Eigenlijke neusholte (nasale fossa)
Vesti bulum nasi
• Overgang huid en eigenlijke neusholte
• Begrensd door septum (zonder kraakbeen/bot) en neusvleugels
• Meerlagig verhoornd plaveiselepitheel met zweetklieren, sebumklieren en vibrissae
→ meerlagig niet-verhoornd plaveiselepitheel
→ cuboidaal tot columnair epitheel
→ pseudomeerlagig trilhaarepitheel
= respiratoir epitheel
Nasale fossa
• Respiratoire mucosa = respiratoir epitheel op een sterk gevasculariseerde lamina
propria die sereuze en muceuze klieren bevat
• Neusseptum
– Distaal hyalien kraakbeen
– Proximaal bot
• 3 conchae < os ethmoidale
– Onderste en middenste bekleed met respiratoir epitheel
– Bovenste bekleed met reukepitheel
Nasale mucosa
3
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