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Summary Cell mediated and Humoral immunity notes
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Atonement/
T LYMPHOCYTES couiabe
•
Made bone Macrophage ( antigen
•
-
marrow
Matures presenting cell )
thymus gland
• -
p
Surface receptors ( glycoproteins) Body invaded by
• .
specific for particular cell
→
antigen
↳
only if presented virus ( parts cell surface )
with self protein on
ANTIGEN CLONAL CLONAL
PRESENTATION SELECTION EXPANSION
- cytokines
i
.
antigen
Each T different receptor Activated T
.
macrophage engulf processes lymphocyte lymphocyte d
•
,
→ .
and presents antigen •
complementary receptor bind, →
macrophage ,
divided many times ( mitosis )
↳ with ↳
self protein macrophage releases cytokines forms clones -
identical T cells
↳ activates specific T lymphocyte
T HELPER LYMPHOCYTES e**
secrete INTERLEUKIN S ( cytokines ) Stimulate B
.
lymphocytes for specific
•
tsryeiegyiinnge , .
antigen
bind target cells Stimulate production
affiliates
.
↳ →
specific receptors on . other types T cell
Act short distances d cones Stimulates macrophages
•
engulf pathogens
•
→
-
, .
T KILLER LYMPHOCYTES
it
it binds to
•
Destroys cell
→
produces perform ( protein )
•
chemical
↳ creates pores in cell membrane →
freely permeable
T MEMORY CELLS T REGULATOR CELLS
blood
°
Suppress
•
Remain in immune
system
Quick effective repeat response ( second encounter Stop immune response after pathogen removed
•
.
+
antigen ) preventing autoimmunity
.
with same
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