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Summary Chapter 17 - The Cell Cycle
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Samenvatting van hoofdstuk 17 van MBOC2
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Molecular Biology of The Cell, 7th Edition
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Chapter 17: The Cell Cycle A new cell can only be formed by cell division
o needed to replace cells that die
o passing on its genetic information to the
next generation of cells
cell cycle = cycle of duplication and division
essential mechanism by which all living things
reproduce
Overview of the cell cycle
Cell cycle: duplicate vast amount of DNA in the
chromosomes and then segregate the copies into
two genetically identical daughter cells
S phase chromosome duplication
o sister chromatids
sister-chromatid cohesion
M phase mitosis
o 1. mitosis / nuclear division
o 2. cytokinesis / cytoplasmic division
o sister chromatids are attached to mitotic spindle = metaphase
anaphase separates sister chromatids
telophase segregated chromosomes are packaged into separate
nuclei
Phases of the eukaryotic cell cycle:
G1 S G2 M
S phase DNA synthesis – chromosome duplication
M phase mitosis; nuclear division – chromosomes will be
separated into to daughter cells
o cytokinesis = cytoplasmic division
G1 phase rest phase – steady state
o gap phase
G2 phase no
synthesis is taking place
– preparation; all
components needed for
mitosis are collected
and being prepared;
ensure that conditions
are suitable
interphase = G1, S, and
G2 together
Start / restriction point
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