Dit document bevat een overzicht van alle onderwerpen van bio informatica gegeven in academiejaar .
Ik heb hiervoor een overzicht gemaakt van alle algoritmes en dit al kort uitgelicht.
Verder bevat het per les en practica een overzicht van de belangrijkste onderdelen en verwijzingen naar de dia...
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Overzicht Technieken.............................................................................................................................4
Les 1.......................................................................................................................................................7
Getting started....................................................................................................................................7
Expectations.......................................................................................................................................8
Les 2.......................................................................................................................................................9
Basic...................................................................................................................................................9
Data opslag.....................................................................................................................................9
Algoritmes..........................................................................................................................................9
Principe van classificatie...................................................................................................................10
Confusion matrix..........................................................................................................................10
ROC analyse..................................................................................................................................10
Graaf theorie....................................................................................................................................11
Basis definities..............................................................................................................................11
Shortest path................................................................................................................................11
Computationele complexiteit...........................................................................................................11
Travelling salesman problem........................................................................................................11
Complexiteit klassen.....................................................................................................................11
Numerieke optimalisatie..............................................................................................................12
Les 3......................................................................................................................................................13
Introduction......................................................................................................................................13
Pairwise alignment.......................................................................................................................14
Begrippen homologie en similariteit.............................................................................................14
Dot matrix methode.........................................................................................................................15
Global Alignment NW.......................................................................................................................15
NW stappen..................................................................................................................................15
Local Alignment SW..........................................................................................................................16
Substitution matrices........................................................................................................................17
PAM..............................................................................................................................................17
BLOSUM........................................................................................................................................18
Les 4......................................................................................................................................................20
Introduction......................................................................................................................................20
Uitdagingen..................................................................................................................................20
Dynamic............................................................................................................................................20
Lipman MSA algoritme.................................................................................................................20
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