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B06IMM Samenvatting Immunologie
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B06IMM Samenvatting Immunologie Leerjaar 2 Tentamen gehaald met een 8, door deze samenvatting
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Inhoud1. Inleiding..............................................................................................................................................3
1.1. Onderscheid tussen binnengedrongen pathogenen....................................................................3
1.2. Afweer linies................................................................................................................................3
2. De cellen van het immuunsysteem.....................................................................................................4
2.1. Cellen van het aangeboren immuunsysteem...............................................................................5
2.2. Cellen van het verworven immuunsysteem.................................................................................6
3. Cellulaire vs humorale immuniteit......................................................................................................7
4. Aangeboren vs verworven immuniteit...............................................................................................7
5.1. Barrières......................................................................................................................................9
5.2. Complement systeem................................................................................................................10
5.2.1. Routes en activatie.............................................................................................................12
5.2.2. Complement activatie.........................................................................................................13
5.2.3. Effectorfuncties van het complementsysteem...................................................................13
6. Herkennen van pathogenen.............................................................................................................14
6.1. Pathogen-associated molecular patterns (PAMPs)....................................................................15
6.2. Pattern Recognition Receptors (PRRs).......................................................................................16
6.3. Na de pathogeen-herkenning....................................................................................................18
7. Fagocytose........................................................................................................................................20
7.1. Communicatie............................................................................................................................20
8. Benodigdheden voor bestrijding van bepaalde pathogenen............................................................22
9. Lymfoïde organen.............................................................................................................................24
9.1. Primaire lymfoïde organen........................................................................................................24
9.2. Secundaire lymfoïde organen....................................................................................................24
10. Ontwikkeling, selectie en training van T-lymfocyten......................................................................25
10.1. T-cel ontwikkeling en selectie..................................................................................................26
11. Activatie T-lymfocyten....................................................................................................................27
11.1. Activatie van Tn cellen door DCs..............................................................................................27
12. Immuniteit tegen intracellulaire pathogenen.................................................................................30
12.1 Cytotoxische T-lymfocyten.......................................................................................................31
12.2. Natural-killer cellen.................................................................................................................33
13. B-lymfocyten en antilichamen........................................................................................................35
13.1. Antilichamen............................................................................................................................35
, 13.1.1.Fc= effector kant................................................................................................................36
13.1.2. Genetica van antilichamen...............................................................................................38
13.1.3. Effector functies van antilichamen....................................................................................39
13.2. Antigenen................................................................................................................................40
13.3. B-cel ontwikkeling....................................................................................................................41
14. Immuun tolerantie en regulatie......................................................................................................42
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