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Sumario Potencial de membrana en reposo de las neuronas
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Resumen del potencial de reposo de las neuronas
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Test Bank -Guyton And Hall Textbook Of Medical Physiology (Guyton Physiology) 14th Edition by John E. Hall, and Michael E. Hall { Hall , 2020}
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Guyton and Hall Textbook of Medical Physiology 14th Edition Test Bank by John E. Hall
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Test Bank For Guyton and Hall Textbook of Medical Physiology 14th Edition By John E. Hall; Michael E. Hall | | 9780323597128 | Chapter 1-85 | Complete Questions And Answers A+
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POTENCIAL DE MEMBRANA EN REPOSO DE LAS NEURONASEl potencial en reposo de la membrana se establece en función de los
potenciales de difusión, la permeabilidad de la membrana y la
naturaleza electrógena de la bomba sodiopotasio. Potencial de
difusión de potasio. El elevado flujo de iones potasio desde el interior
al exterior de la célula, 35:1, produce un potencial de Nernst de -94
mV de acuerdo con la ecuación de Nernst.
Potencial de difusión de sodio. La relación de los iones sodio entre el
interior y el exterior de la membrana es de 0,1, con lo que se obtiene
un potencial de Nernst calculado de +61 mV.
Permeabilidad de la membrana. La permeabilidad de la membrana de
la fibra nerviosa al potasio es 100 veces mayor que al sodio, así que la
difusión de potasio alto valor de permeabilidad en la ecuación de
Goldman nos permite obtener un potencial de membrana interna de -
86 mV, que se acerca al potencial de difusión de potasio de -94 mV.
Naturaleza electrógena de la bomba sodio-potasio (Na+-K+). La
bomba Na+-K+ transporta tres iones sodio hacia el exterior de la célula
por cada dos iones potasio bombeados hacia el interior, lo que
provoca la pérdida continuada de cargas positivas desde el interior de
la membrana. Por tanto, la bomba Na+-K+ es electrógena porque
genera un déficit de iones positivos dentro de la célula, con lo que se
crea una carga negativa de unos -4 m V en el interior de la membrana
celular.
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