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By: ano2015anoniem • 3 year ago
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HoeEn is
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Het Ebolavirus (EBOV) is een van de meest virulente ziekteverwekkers Het
die de mens kan infecteren.[1] In de afgelopen vier decennia zijn er vijf Glyc
uitbraken geweest van Ebolavirussen waarbij het virus overspringt van nucl
dier op mens.[1] Het Ebolavirus is gekenmerkt door de helix structuur en [4]
De
het enkelstrengs RNA genoom en behoort daardoor tot de filovirussen
en de orde mononegavirales.[2] Filovirussen (waaronder het ebolavirus)
staan er om bekend hemorragische koorts te veroorzaken en interne
bloedingen. Dit wordt veroorzaakt door dat het Ebolavirus is staat is om
niet alleen normale cellen te infecteren maar ook cellen van het
aangeboren immuunsysteem.[3] Cellen zoals macrofagen, NK-cellen en
dendritische cellen worden geïnfecteerd en gaan daarna dood, hierdoor
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